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02-13-2012 at 11:17 AM
jw87
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Anyone taking Ondansetron (generic Zofran)?

I was prescribed 4mg ondansetron today for my nausea and vomiting but I'm a little upset because when I had to go to the ER a week ago for vomiting they gave me zofran through my IV and I felt sooo much better.  They sent me home with a small prescription of dondansetron... but it didn't seem to work.

Has anyone noticed a difference in the generic vs. namebrand?  If you're on odansetron has it been helping?


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02-13-2012 at 11:43 AM
VanessaB24
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it helped the first night i took it but i was also constipated the next day but i did take it again the same day @ 11am to be nauseous by 4 again so it didn't work but i thought i'd give it another try last night and it helped a bit but not too much because i felt nauseous... this morning i was fine and i haven't taken it but i feel nauseous now a bit and i ate a little

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02-13-2012 at 11:48 AM
kbradshaw9
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4mg did nothing for me. They bumped my up to 8mg every 8 hours. Try that and see if it works.

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02-13-2012 at 11:57 AM
SaucyKell
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Its not the generic vs. brand name, its the route. IV meds are often more effective than PO (by mouth).

(PS zofran is the mildest anti-emetic, maybe they should give you phenergan? It is stronger but may make you drowsy) 


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02-13-2012 at 1:37 PM
tch81
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It's working beautifully for me.  I forgot to take it one day & paid the price!

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02-13-2012 at 2:32 PM
lzygrl42
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Saucykel is correct..IV route isn't necessarily more effective, it is just fast relief but also it is a shorter relief because it is directly injected into your bloodstream where as the pill form slowly is dissolved into it..So the reaction time with the PO (by mouth) form is slower but should lasts longer..I am on it 2 times a day..some days I feel I need another dose in the afternoon but some days the 2 times a day is enough..call you OB and get approval to increase it 8mg?

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02-13-2012 at 3:04 PM
SaucyKell
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lzygrl42:
Saucykel is correct..IV route isn't necessarily more effective, it is just fast relief but also it is a shorter relief because it is directly injected into your bloodstream where as the pill form slowly is dissolved into it..So the reaction time with the PO (by mouth) form is slower but should lasts longer..I am on it 2 times a day..some days I feel I need another dose in the afternoon but some days the 2 times a day is enough..call you OB and get approval to increase it 8mg?

If you get 4mg IV vs. 4mg PO it is slightly more effective because none is lost through digestion... also with Zofran it is not as effective if you are already nauseated when you take it vs. if your nausea is under control and are taking it on a regular basis.  


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02-13-2012 at 9:33 PM
jenwill
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There is no difference in generic vs name brand. They are the same medicine. I work in the ER and we give generic zofran IV, likely that is the same thing you had but they told you they were giving you Zofran b/c that's the name you know of it. I never say "I'm giving you Ondansetron"...no one would know what I was talking about.
Ditto PP's-it's the route. Fast relief via IV. Did they give you a pill you swallow or one that dissolves under your tongue (ODT)? If they gave you a pill to swallow, you may want to inquire about getting the ODT version-it's absorbed faster. HTH!

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02-14-2012 at 12:21 AM
irishgirlm...
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SaucyKell:

Its not the generic vs. brand name, its the route. IV meds are often more effective than PO (by mouth).

(PS zofran is the mildest anti-emetic, maybe they should give you phenergan? It is stronger but may make you drowsy) 

Actually, zofran is a stronger antiemetic.  And, safer during pregnancy.  Zofran is a category B drug and phenergan is a category C drug.  I would stick with the zofran.  Generic is the same as name brand.  You may need a higher dose and it likley worked more quickly in the ER b/c it was given IV.   

 
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