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11-05-2012 at 7:41 PM
jmb7712
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Joined on 10-25-2009
4,914 Points
jmb7712 is not online. Last active: 05-24-2013, 9:28 PMNewbie

Karyotyping/genetic testing/infertility thoughts? New to this RE thing! Please help!

Hi Ladies! Our RE recommended we may need to have the genetic testing and karyotyping done. However they said this is something rarely covered by our insurance. Does anyone have any idea how much this may cost us out of pocket? Do you guys suggest this and what would this show? We are new to this infertility route... in the early phase and haven't done a cycle yet- still gathering data and test results. How long does testing generally take before they do a cycle? Thanks!! 

 

Any other suggestions/comments about this infertility route extremely welcomed! So far abnormal SA is only thing popping up (1% normal morphology). Waiting results of clotting disorder/immune disorder panel, negative for CF carrier, and waiting for the return of AF for HSG. Normal like clock work cycle and ovulation cycle to my knowledge. 

 

Please send me advice and thoughts! I REALLY would appreciate it I'm so scared :( 


Me (26) DH (27) ....Married 9/10/11....TTC since 1/2012........ BFP #1 March 2012...M/C #1 April 2012 with D&C( Our Angel Baby Boy) at 8.5 weeks....BFP #2 October 2012.....Natural M/C #2 October 2012 at 5w5d.....*RE and Workup shows only mild MFI*.....First IUI cycle started 12/14/12 Gonal-F, Ovidrel, Crinone....BFN.....IUI cycle #2 started 1/9/2013..... BFP with great betas and HB.....loss of HB found at 7w apt. M/C #3 at 6w5d, D and C karyotyping showed Trisomy 4, rare and one time chromosomal error and our 2nd angel baby boy. IUI #3 5/9/2013... BFP#4 11dpiui!!!.....beta #1 14dpiui... 327!!!!...... Stick baby, stick!!!!!! . . . "Never in my arms, but forever in my heart. Gifts too precious for this Earth."......4/23/12......10/25/12.......2/26/13...... ...... Daisypath Anniversary tickers ~~~~~~~~~~~~~~~~~~~~~~~~~~ ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ **I have died everyday waiting for you, darling don't be afraid, I have loved you for a thousand years, and I'll love you for a thousand more.** 
11-05-2012 at 8:16 PM
bhead81
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Joined on 05-25-2008
Queen Creek, AZ
5,651 Points
bhead81 is not online. Last active: 05-22-2013, 6:31 PMSilver
Our RE office runs the genetic testing through a place that offers a $99 max OOP for the testing.  I am glad we had this done as I came up a carrier for something and now we are just waiting to see if DH is as well. 

Brenda & Phillip 10/10/2009

After 6 years of failed cycles, we were blessed with our little man through adoption.

IVF - Jan 2013
S/PAIF welcome
~~TTC Buddy kristie2422~~
 
11-05-2012 at 9:04 PM
ThereBeDra...
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Joined on 12-30-2011
8,028 Points
ThereBeDragons is not online. Last active: 05-16-2013, 4:57 PMBronze

The costs out of pocket are really going to vary. Every clinic has a slightly different list of tests on their RPL panel and the labs have different prices per test. Every insurance will cover different tests- or no tests at all.

Ask your RE if they have an out of pocket agreement with a local lab to help patients offset the cost of testing. Ask the lab if they offer a discount for cash pay. It's a good rule in general to ask any provider which you see OOP if they offer a cash discount. 

I am 100% OOP for everything related to infertility and pregnancy. My clinic works with Lab Corp and I can opt to pay the clinic and have lab corp bill the practice. My payment is significantly reduced. My (very in depth) RPL was going to run about 4500$ if I paid the lab... But cost me only 1500$ through the clinic. 

My RPL came back with no answers. That happens sometimes. They looked for chromosomal abnormalities in both me and DH. They checked me for autoimmune diseases which could impact my ability to carry a pregnancy. They checked for a number of clotting disorders which could cause a loss. They checked for a few genetic markers that are associated with a risk for loss. They have run every test possible on me and my diagnosis is the worst case of bad luck my docs have ever seen (especially after my loss this weekend... Which absolutely no one expected) 

Most of the things they check for will impact your treatment. They'll put you on blood thinners if you have a clotting disorder. You can be treated to reduce the impact of some autoimmune diseases. You can do pre-implantation genetic diagnosis to put back only chromosomally normal embryos if one of you has a chromosomal translocation. 

The majority of a RPL panel will come back in less than a week. Karyotyping may take two to four weeks depending on the lab. If any of the results come back positive there may be additional testing. All in all the testing period can take 3-4 weeks to get everything from the RPL to an HSG to the SA to maybe even a hysteroscopy scheduled and all the results returned. If anything gets delayed it could be more like 6-10 weeks for the testing phase. Then, depending on the type of treatment (IUI or IVF) the cycle itself may need 3-4 weeks of birth control prior to getting the fertility meds running.

It's a process. 



Friends for 16 years. Married 9. TTC since January 2009
2010: Diagnosis: Severe MFI & Annovulation.
2011: IVF #1: Transferred 2 day 5 blasts- c/p.
FET #1: Transferred 2 day 5 blasts- Miscarriage of a singleton at 6weeks.
FET #2: Transferred 1 day 5 blast- BFN.
2012: IVF #2: Transferred 2 day 5 blasts- BFN.
FET#3: Transferred 2 day 5 blasts- Lost "Peanut" to PTL/IC at 17weeks.
2013: One frozen embryo left. My heart is still healing, but we may try again next year. Lilypie Angel and Memorial tickers
Formerly ecleptic. Dum spiro, spero.  
11-06-2012 at 8:27 AM
MsGMChick
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Joined on 01-27-2009
VA
8,011 Points
MsGMChick is not online. Last active: 04-21-2013, 8:40 AMSilver

I had the RPL panal done as well as karyotyping for MH and I.. all the results were normal. I'm still glad we got it done because if it had found something, we could be proactive. 

As for the cost, I honestly don't know. My dr wrote the order for me to take to Quest and they drew it all and billed my insurance. I have yet to get a bill. FWIW- all the icd9 codes they used were non IF related.

_______________________________________________________________

ThereBeDragons- I'm so sorry to see you here and for your loss. ((hugs))  


. .
|| 3 years TTC, 2 M/Cs 4 failed IUIs, 1 failed IVF...
and we're moving on! Domestic Infant Adoption ||


He who has a why to live, can bear almost any how... 
11-06-2012 at 8:43 AM
BzeetyD
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Joined on 07-29-2010
Twin Cities, MN
22,705 Points
BzeetyD is not online. Last active: 05-25-2013, 7:47 AMSilver

Our insurance covered both RPL and karyotyping but I can tell you that the karyotyping was around $3000 as our insurance co sent us the check and then we sent it on to the lab.

Karyotyping shows if you and your partner have DNA that don't jive together and would most likely keep creating miscarriage situations.

These tests are all blood tests and for us the results were back in about 2 weeks. You could start a cycle without knowing the results, but it might be best to wait.

I hope this helps.


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues
Long story: trying on our own + testing testing testing with 6 rounds of Clomid , more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal

Moving on to IVF.

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!! FET 5/31/13



"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
11-06-2012 at 7:11 PM
cupcake201
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Joined on 11-16-2011
5,238 Points
cupcake201 is not online. Last active: 05-23-2013, 9:15 PMBronze
My RE ordered karyotyping and genetic testing at our first appointment, due to my two early losses.  It can test to see if there is a genetic reason for recurring pregnancy losses.  The testing was covered by insurance and the karyotyping revealed my husband had a balanced chromosomal translocation, so we are moving forward with IVF w/ PGD.  

Image and video hosting by TinyPic

TTC#1 since 4/11 : m/c in 9/11 & 11/11
DH dx with Balanced Translocation 5/12
10/12 IVF#1-7R, 3M, 3F- No transfer - Froze 2.
IVF#2 1/13 - 11R, 10M, 6F, no transfer
IVF#3 4/13 - 8R, 6M, 6F, 1 passed PGD and was transfered 5/2/13
S/PAIF Welcome
 
11-09-2012 at 2:15 PM
MamaGigi80
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Joined on 08-09-2012
1,143 Points
MamaGigi80 is not online. Last active: 05-06-2013, 2:55 PMNewbie

I went to my RE this morning, I have had two recent failed IVF cycles.  I am 32 years old and not producing enough eggs/good quality eggs.  They drew blood for karotype and fragile X testing.  I am concerned as my family has a hx of mental retardation associated with abnormal amino acid levels, so I am hoping that this is not effecting my ability to get pregnant. The results should be back in 10 days.  We should be starting my next cycle in January!



Trying to become a Single Mother By Choice! 9/4/12 ER - 2 eggs, neither fertilized 10/17/12 ER 2 eggs, one immature one fertilized, 2 day transfer on 10/19/12 
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