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11-15-2012 at 11:44 AM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze

D@mn you, metformin

I feel pretty confident in saying that this is the worst IF drug I've taken. Mentally, I suppose Clomid messed with my head the worst (I did use to call myself The Incredible Hulk), but this is physically uncomfortable to a degree no other medication has been. I really don't want to gross anyone out, but let's just say that I have pretty much have every gastrointestinal symptom you can think of and I'm getting stomach cramps, too. I was definitely warned that this was a possibility so I can't say I'm shocked, but it feels like the Battle of the Bulge is being waged in my GI tract right about now.

I spend more time in the bathroom than Lindsay Loh.an.

The nurse told me to call and ask to be taken off the meds if it became "unbearable," the definition of which I'm debating right now. 


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 11:50 AM
DoublePort...
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How funny...I use to call myself the Hulk when I was on Clomid too. lol It gave me major rage issues. Angry I would give ((hugs)) but I don't want to get too close. Tongue Tied  Will Pepto or anything like that help? FX it gets better quick!!

 

No wonder my cousin looses weight while she's taking it...
Image and video hosting by TinyPic
Me: 29 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!
Him: 28 ~ perfect swimmers
Laparotomy with partial oophorectomy 8/2009 to remove cysts/endo. Stopped BCP 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
IVF #1:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
BCP to manage endo from 10/2012 to 12/2012.
5/2013 Waiting for Donor Embryos

PAIF/SAIF always welcome!
If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus! 
11-15-2012 at 11:51 AM
Maybe Jole...
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Maybe Joleisa is not online. Last active: 05-13-2013, 8:41 PMSilver
Are you on the ER (extended release) white tabs? I'm on Met for fasting IR and have fortunately experienced no side effects.  I heard that people who are prescribed the non-ER type have all the symptoms you are describing--sounds awful and I hope you get some relief soon.

Image and video hosting by TinyPic
Me: 40, DH: 40 Married since 4/2009, TTC since 10/2010
FSH= 5.4, AFC= 11 Dx: Unexplained w/2% morphology
IUI 1-3: Clomid, Gonal F, Ovidrel + Prometrium = BFN
Acupuncture starting January 2012; IUI 4-5: Gonal F, Ovidrel + Prometrium = BFFN
IVF #1 (Antagonist) w/ICSI & AH: ER 8/7/12--7R/4M/4F; ET 2-8-cells + 1-7-cell embies= BFN
IVF #2 (MDLF)w/ICSI & AH: ER 11/26/12--23R/14M/6F ET 11/29 1 early morula + 2 8-cells; Beta 1 (15dp3dt)= 408; Beta 2 (17dp3dt)= 649 Beta scare :/ ; Beta 3 (19dp3dt)= 1485; 1st u/s 12/28/12= 1 sac with 2 HBs 113bpm EDD= 8/19/13; MIssed MC of identical twin boys D&C @ 8w3d on 1/10/13

PAIF/SAIF welcome!
 
11-15-2012 at 11:59 AM
Scoop77
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DoublePortion:

I would give ((hugs)) but I don't want to get too close. Tongue Tied 

...

No wonder my cousin looses weight while she's taking it...

Stay away! Save yourself!

And if I were losing weight, it would almost be worth it. I'm compiling a list of terrible things I've undergone to get pregnant so that I may harass any future children I have on the regular with a dramatic reading from the list. "AND THEN, I SPENT A MONTH ON THE TOILET!"

TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 12:02 PM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze

Maybe Joleisa:
Are you on the ER (extended release) white tabs? I'm on Met for fasting IR and have fortunately experienced no side effects.  I heard that people who are prescribed the non-ER type have all the symptoms you are describing--sounds awful and I hope you get some relief soon.

I'm not on extended release, no. I wonder if I could get switched to those? I also am taking three pills a day, which might not help. 


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 12:05 PM
Lacyj67
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Lacyj67 is not online. Last active: 06-19-2013, 9:26 AMBronze
After being on met for three months I had to go off it. It gave me unbearable stomach pains in the middle of the night! Be careful I've read that it can be dangerous with some of those symptoms!! Sorry that sucks!!! GL
Me 32 and DH 37 married in aug. 2002 Did 5 round of clomid 2010 =BFN High levels of NK CELLS DX sept.2012 DOR:# 0.02 IVF #1 May 2012 ER 4, EF 2, ET 2 =BFN Hysteroscopy 7/12/12 D&C preformed and one Polyp removed MINI IVF Oct.2012 Cancelled 10-27-12 Ivf #3 Antagonist Protocol April 2013 Ivf #3 Cancelled April 22nd 2013 Currently doing a DE CYCLE. ER around mid july and FET for me sept. 3 rd 2013. Everyone Welcome  
11-15-2012 at 12:07 PM
DoublePort...
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Scoop77:
DoublePortion:

I would give ((hugs)) but I don't want to get too close. Tongue Tied 

...

No wonder my cousin looses weight while she's taking it...

Stay away! Save yourself!

And if I were losing weight, it would almost be worth it. I'm compiling a list of terrible things I've undergone to get pregnant so that I may harass any future children I have on the regular with a dramatic reading from the list. "AND THEN, I SPENT A MONTH ON THE TOILET!"

lol They'll go to kindergarten and they won't know their ABC's but they will have "Mom's List of Sufferings" memorized!

I look forward to the day a teenage brat tells me "I wish I was never born"! Boy will they get it!! Then I'll set up a payment plan so they can pay me back for all the $$ I spent for them to be born.

Image and video hosting by TinyPic
Me: 29 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!
Him: 28 ~ perfect swimmers
Laparotomy with partial oophorectomy 8/2009 to remove cysts/endo. Stopped BCP 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
IVF #1:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
BCP to manage endo from 10/2012 to 12/2012.
5/2013 Waiting for Donor Embryos

PAIF/SAIF always welcome!
If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus! 
11-15-2012 at 12:08 PM
Crystal120...
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OMG this made me actually lol. Its so crazy what we willingly subject ourselves to. I sure hope your tummy issues settle down, being stuck on the toilet is one of the worst. Good luck!!
Married 9-10-11
Together 6 years before marriage
Me 26 DH 28
TTC since 9/2011
Dx endo 2007 Sx laparoscopy
End bcp 9/2011
Dx annovulatory, DOR, Low AMH
Hysteroscopy due to polyp 2-1-12
IUI#1-3 Cancelled due to low response
IUI#4 BFFN
IVF#1 8/30 Beta#1 256, 8/31 Beta#2 482 BFP!! M/C 5w3d
FET#1 Cancelled due to uterine fluid and thin lining
FET#1.2Cancelled due to abnormal bleeding
Hysteroscopy 12/28/12 All clear
FET#1.3 2/2013 Cancelled
FET #1.4 3/19 BFFN
Semi natural cycle 5/13 BFN
IVF&FET June 2013
Good Luck to All!!
Crystal
Image and video hosting by TinyPicImage and video hosting by TinyPic  
11-15-2012 at 12:14 PM
Scoop77
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Lacyj67:
Be careful I've read that it can be dangerous with some of those symptoms!!

Thanks, I've heard that, too. I'll keep in touch with the clinic if things stay this bad.


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 12:24 PM
Love4Labs3...
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Love4Labs326 is not online. Last active: 06-18-2013, 9:05 PMBronze
Did you start out at 3 times a day right off the bat or did you work your way up to that.  I know normally they want to start with a small dosage and then slowly increase it as your body tolerates.  Or maybe what other's suggested, change the drug to ER or the similar.  I hope you're feeling better soon.
230737_2003784652243_5215174_n
Mr. & Mrs. since March 26, 2011
TTC #1 since May 2011 ~ Everyone Welcome
ME(29) ~ DOR due to chemo and radiation, FNH, Hypothyroid
Ewing's Sarcoma ~ 9/30/92 ~ CURED!!!
DH(29) ~ Oligoasthenoteratozoospermia, Low testosterone
7.5 million spermies on ice!
IVF/ICSI/AH planned for June 2013 ~ Delayed
Vivelle, Progesterone, HGH, Dexamethasone
Femara, Bravelle, Menopur, Ganirelix
 
11-15-2012 at 12:33 PM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze

Love4Labs326:
Did you start out at 3 times a day right off the bat or did you work your way up to that. 

Yeah, they started me out with once a day, then went up after a while to twice a day and then after another period went up to three times a day.


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 12:34 PM
Ecarabeo21...
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Ecarabeo217 is not online. Last active: 06-18-2013, 8:27 PMBronze
Scoop77:

Maybe Joleisa:
Are you on the ER (extended release) white tabs? I'm on Met for fasting IR and have fortunately experienced no side effects.  I heard that people who are prescribed the non-ER type have all the symptoms you are describing--sounds awful and I hope you get some relief soon.

I'm not on extended release, no. I wonder if I could get switched to those? I also am taking three pills a day, which might not help. 

WORK YOUR WAY UP TO 3 PILLS!!!! Start with one and she. The symptoms subside a a second, then the third.  Slower process but 3 for. The word go is intense! Good luck! 
Married 2007 3 Clomid IUIs -- BFNs IVF #1 never made it to transfer On "egg health" cocktail DHEA/CoQ10/FRC/Pregnitude/Melatonin Starting IVF #2 for Feb 2013 Follistim/Menopur/Ganirelix Cancelled mid-cycle due to high P4 levels early on. OCPs again for IVF 2.5 mid-March. "You may have to fight a battle more than once to win it." -- Margaret Thatcher  
11-15-2012 at 12:34 PM
Love4Labs3...
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Love4Labs326 is not online. Last active: 06-18-2013, 9:05 PMBronze
Scoop77:

Love4Labs326:
Did you start out at 3 times a day right off the bat or did you work your way up to that. 

Yeah, they started me out with once a day, then went up after a while to twice a day and then after another period went up to three times a day.

Was it this bad with just twice a day?
230737_2003784652243_5215174_n
Mr. & Mrs. since March 26, 2011
TTC #1 since May 2011 ~ Everyone Welcome
ME(29) ~ DOR due to chemo and radiation, FNH, Hypothyroid
Ewing's Sarcoma ~ 9/30/92 ~ CURED!!!
DH(29) ~ Oligoasthenoteratozoospermia, Low testosterone
7.5 million spermies on ice!
IVF/ICSI/AH planned for June 2013 ~ Delayed
Vivelle, Progesterone, HGH, Dexamethasone
Femara, Bravelle, Menopur, Ganirelix
 
11-15-2012 at 12:55 PM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze
Ecarabeo217:
Scoop77:

Maybe Joleisa:
Are you on the ER (extended release) white tabs? I'm on Met for fasting IR and have fortunately experienced no side effects.  I heard that people who are prescribed the non-ER type have all the symptoms you are describing--sounds awful and I hope you get some relief soon.

I'm not on extended release, no. I wonder if I could get switched to those? I also am taking three pills a day, which might not help. 

WORK YOUR WAY UP TO 3 PILLS!!!! Start with one and she. The symptoms subside a a second, then the third.  Slower process but 3 for. The word go is intense! Good luck! 

I did work my way up to three. I didn't start out taking three a day.


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 12:57 PM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze
Love4Labs326:
Scoop77:

Love4Labs326:
Did you start out at 3 times a day right off the bat or did you work your way up to that. 

Yeah, they started me out with once a day, then went up after a while to twice a day and then after another period went up to three times a day.

Was it this bad with just twice a day?

The first day or two of each step in the process was pretty bad. The first time I took a pill, I had a really hard time for a day or so. And the same with the first time I was on two pills a day. I just recently increased to three a day so I'm thinking it might improve as my system gets used to the increased dose. If not, then I'll consider whether to go off them entirely. I think I'll give it another day or two before deciding.


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 1:02 PM
lisa41982
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lisa41982 is not online. Last active: 04-02-2013, 6:20 PMNewbie

Are you taking them all at once and at night? This seemed to be the best option for me. 

Hope it improves soon!

 
Dx PCOS 2006 - on Metformin
Dx Hypothyroid 2009 - on Synthroid
TTC since 12/2009
DH - Low Sperm Count

IVF with ICSI Cycle #1 - October/November- 10/11 Begin Lupron, 10/20 Begin 300iu Gonal-F, Trigger 10/31, ER 11/2, 12 retrieved, 11 mature, 6 fertilized, ET 11/5 - 2 Grade 1 8 cells, 2 frozen blasts (5BA, 3BB), Beta #1 @ 8dp3dt: 7, Beta #2 @ 11dp3dt: 2 :(

IVF with ICSI Cycle #2 - January - 12/30 Begin Lupron, 1/8 Begin 300iu Gonal-F, ER 1/20, 13 retrieved, 11 mature, 6 fertilized, ET 1/25 - 2 blasts (grades 4BA, 1)

Everyone Welcome

Image and video hosting by TinyPic Image and video hosting by TinyPic 
11-15-2012 at 1:36 PM
Scoop77
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Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze
lisa41982:

Are you taking them all at once and at night? This seemed to be the best option for me. 

Hope it improves soon!

The pharmacist said to take one with each meal, which is what I've been doing.

Thanks for all the help, everyone. At least I have some questions now that I can ask the clinic about switching things up if this continues. 


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 2:34 PM
Love4Labs3...
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Love4Labs326 is not online. Last active: 06-18-2013, 9:05 PMBronze
Good luck!!
230737_2003784652243_5215174_n
Mr. & Mrs. since March 26, 2011
TTC #1 since May 2011 ~ Everyone Welcome
ME(29) ~ DOR due to chemo and radiation, FNH, Hypothyroid
Ewing's Sarcoma ~ 9/30/92 ~ CURED!!!
DH(29) ~ Oligoasthenoteratozoospermia, Low testosterone
7.5 million spermies on ice!
IVF/ICSI/AH planned for June 2013 ~ Delayed
Vivelle, Progesterone, HGH, Dexamethasone
Femara, Bravelle, Menopur, Ganirelix
 
11-15-2012 at 2:37 PM
MrsGlitter...
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MrsGlitteryHooks is not online. Last active: 06-19-2013, 10:22 AMBronze

I had the sh!ts for about 6 weeks on Metformin and lost 18lbs then it leveled off. I used to suck at taking them and then switched to extended release and take all 3 pills at night. Having so much rrhea is a good sign it's working. Switch to extended release (they are a $4 generic at Target Pharmacy) and it will get better I promise.

The constant diarrhea will go away. Having horrendous gas and diarrhea that reeks like burning tires is totally normal on this drug. You'll soon learn what food will have you chained to the toilet and what won't.


TTC since October 2008My Infertility History is listed in my Blog
My Blog
BabyFruit Ticker 
11-15-2012 at 3:05 PM
Scoop77
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MrsGlitteryHooks:

I had the sh!ts for about 6 weeks on Metformin and lost 18lbs then it leveled off. I used to suck at taking them and then switched to extended release and take all 3 pills at night. Having so much rrhea is a good sign it's working. Switch to extended release (they are a $4 generic at Target Pharmacy) and it will get better I promise.

The constant diarrhea will go away. Having horrendous gas and diarrhea that reeks like burning tires is totally normal on this drug. You'll soon learn what food will have you chained to the toilet and what won't.

Oh, FANTASTIC! I was hoping that wasn't just a temporary side effect. 


TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 4:13 PM
BzeetyD
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Joined on 07-29-2010
Twin Cities, MN
3,933 Posts
23,744 Points
BzeetyD is online. Last active: 06-19-2013, 4:56 PMSilver

I'm sorry Scoopsy!

And not enjoying the idea of this kind of horrendous side effect/effect. My doc mentioned metformin just this morning to me. AHHHH!

I hope you can bear through it or go back to twice a day or do the extended tabs.

Big hugs and a roll of TP.

 
BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
11-15-2012 at 4:34 PM
Scoop77
Not Ranked
Joined on 08-10-2011
1,032 Posts
10,380 Points
Scoop77 is not online. Last active: 05-21-2013, 3:10 PMBronze
BzeetyD:

And not enjoying the idea of this kind of horrendous side effect/effect. My doc mentioned metformin just this morning to me. AHHHH!

I hope you don't get the same side effects I've had. I think Mr. Scoop is trying to decide whether to try to sneak out of our house in the middle of the night and never return. The good news is, he probably won't have time to take anything with him so I'll get to keep all our DVDs.

TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
11-15-2012 at 5:25 PM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
3,933 Posts
23,744 Points
BzeetyD is online. Last active: 06-19-2013, 4:56 PMSilver
Scoop77:
BzeetyD:

And not enjoying the idea of this kind of horrendous side effect/effect. My doc mentioned metformin just this morning to me. AHHHH!

I hope you don't get the same side effects I've had. I think Mr. Scoop is trying to decide whether to try to sneak out of our house in the middle of the night and never return. The good news is, he probably won't have time to take anything with him so I'll get to keep all our DVDs.

Well, that's only fair.

 
BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
11-15-2012 at 11:36 PM
2MamazInSe...
Not Ranked
Joined on 10-21-2012
574 Posts
12,695 Points
2MamazInSeattle is not online. Last active: 06-19-2013, 2:51 PMBronze
I got some major poopsies when I took metformin but found dairy to be the big aggravator. Like one tiny bite and 5 minutes later...ug. It did resolve but took a couple months then no side effects...try to avoid all dairy and see if it helps maybe. I know how you feel :(

[IMG]http://i39.tinypic.com/263g0ex.jpg[/p> Together 7 years and legally married in 2013!
Me: 42 (Excited to carry!) DW: 44
June 2012: First RE appt.due to age + plan to use DS
Sept 2012: Both fallopian tubes removed due to blockage
Dec 2012: Donor Egg/Donor Sperm IVF Cycle - BFP! EDD 8/29/13
Mar 15 2013: Missed miscarriage at 15w4d(discovered at 16w1d via home Doppler).
Mar 22 2013: D&E. Tests showed death due to (fluke) blood clot in umbilical cord. :(
May 24 2013: Hysterscopy to remove uterine adhesion post D&E.
We have three frosties. FET on July 18, 2013!
We live in Seattle and used SRM for our Donor Egg IVF cycle.
Lilypie Angel and Memorial tickers 
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