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11-29-2012 at 1:52 PM
futurehube...
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futurehuber is online. Last active: 05-20-2013, 4:29 PMBronze

XP - MFI and Decision Making (long)

Hi ladies! I should probably introduce myself as I've posted here once before and I'm expecting I might be hopping on the IVF train sometime in the near future.  I have PCOS and we recently also got diagnosed with MFI.  I've been posting on TTTC, but thought I would post this here too.  Thanks so much for any input!  And GL to all those ladies going through an IVF cycle right now!

Here's my XP:

So we officially have an MFI diagnosis. We did SA#1, B2B IUIs and then SA#2 and just got results on that yesterday.  I pretty much knew for sure once we did the IUIs and got our post-wash counts that it was a done deal.  At first we were told everything was bad, but then I was hopeful about motility and morph, but now I'm not again.  Basically this is our history:

SA #1
Count - 6.5 mil
Motility - 25%
Morph - Abnormal per the results summary, but outdated ratings were used per my RE and she actually thought it might not be that bad (SA was done through our HMO medical group, the whole process was a mess)

IUI #1.1
Pre-Wash Count - 7 mil
Pre-Wash Motility - 71%
Post-Wash Motile Sperm - 2 mil

IUI #1.2
Pre-Wash Count - 8 mil
Pre-Wash Motility - 63%
Post-Wash Motile Sperm - 1.8 mil

SA #2 (done through RE's legit lab this time)
Count - 5 mil
Motility - 45%
Morph - 5%

DH had some additional blood work done yesterday ($300 blood work, awesome) and we are waiting to get those results.  Oh and his testosterone at the time of SA#1 was on the lowish side (340 I think?).  He is also getting a referral to a urologist, supposed to get a scrotal ultrasound, etc. 

So this might be a little premature as we have still have to check his stuff out, get results, see the uro, etc., but was just curious for those dealing with MFI out there how you decided to proceed with treatments?  Did you guys do everything in your power to figure out DH's issues and try to fix it?  Did you decide just to move on to IVF somewhat soon because it wasn't looking too hopeful?  Did your RE's/DH's uros give good chances of being able to improve his swimmers and then have luck with IUI? 

I'm asking because 1) I'm the most impatient person in the world, haha, and just want to move forward and be PG as soon as possible (I know, wrong mentality for IF!) and 2) we are 50% covered for diagnosis/treatment and 100% OOP for IUI and IVF.  I feel like spending tons of money and time on trying to work on DH's issues will end up adding up to what we will pay for IVF anyways. And if our chances are still going to be pretty slim with IUI, then why waste the time/money?

Also, the reason I also feel like his quality might not improve much is because DH already does a lot of the stuff people here recommend and all of the websites I Google recommend (and he's been doing this for ages).  He eats super healthy, he takes multi vitamins & Co-Q10, drinks tons of water, wears boxers, doesn't do hot tubs/saunas regularly, etc.  But I do know he might be able to be put on meds, etc.  And there might be other factors (i.e. varicocele, etc) that might be causing this.  So again, this is all pretty premature.  Just wondering what your experiences have been?  Thanks so much!  And sorry this is so long. 
TTC #1 since Sept 2011
Me: 33, DH: 35, DX: PCOS & MFI (low everything)
HSG misdiagnosed Bicornuate or Septate Uterus,
but Saline Ultrasound a month later showed no uterine issues, yay!
IUI #1 Oct/Nov 2012: Clomid (100mg) + Trigger + B2B IUIs (2 mil count & 1.8 mil count) = BFN
IUI #2 Feb 2013: Clomid (100mg) + Trigger + B2B IUIs (2.5 mil & 4 mil count) = BFN
IUI #3 March 2013: Clomid (100mg) + Trigger + IUI (5 mil count) = BFN
IVF #1 w/ ICSI: Long Lupron Protocol - Freeze-All Cycle due to Severe OHSS
ER 4/27, 33 Eggs Retrieved, 13 Frosties, Estimated FET 5/29
All are welcome!

3T May Siggy Challenge - Dream Vacation: Northern Italy  
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11-29-2012 at 2:01 PM
coastalchr...
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coastalchristina is not online. Last active: 05-20-2013, 12:27 PMNewbie

We moved straight to IVF with ICSI due to MFI.  We have <1% chance of getting pregnant on our own or with IUI due to DH's sperm count <5 mil and that IUI would be a waste of our money (OOP for everything).

  DH's horomonal levels were all normal, and the only thing they could find that might be affecting his sperm is that he's a CF carrier.  So the RE and urologist didn't think anything would increase his numbers. 

We had ER yesterday and the fertilization report today was that all 11 mature eggs were fertilized and are doing well.

 Good luck deciding what to do and I hope you get pregnant soon.

BabyFruit Ticker
Me 32 DH 35 Together 10 years, Married 5 years
TTC #1 since 8/2007 with MFI
November 2012 - IVF w/ ICSI #1; 11/28/12 - ER 12 eggs! 11 fertilized! 12/3/12 - ET - transferred 1 AA Blastocyst
 
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11-29-2012 at 2:32 PM
firesiren
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firesiren is not online. Last active: 05-20-2013, 3:51 PMBronze
Welcome! We have severe MFI and it sucks.  Good Luck to you!
Me; 35 DH 32 TTC for over 2 years First mini-IVF Sept 2011... Only 1 egg! ... BFN Switching RE IVF#2 May 2012 9 eggs and only 2 sperm, WTH! BFN IVF#3 Chemical... FML. 2 frosties. SAIF/PAIF ALWAYS WELCOME!!!!!
My Idle Oven Blog!
*~God gives his hardest battles to his toughest solders. Unknown.
 
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11-29-2012 at 4:13 PM
rrdiva1
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rrdiva1 is not online. Last active: 05-20-2013, 9:44 AMSilver

I am so sorry you are dealing with all of this. We have numbers similar to yours, and were told less than 3% to conceive on our own or IUI, so we had to go right to ivf with ICSI. They did put hubs on clomid eod 50mg, just to produce more good sperm for them to pick from for the icsi.

wishing you nothing but the best, and hope they get you a good plan of action! ((((hugs)))))
Married BF 6/29/2002/ TTC Since Aug 2011/ ME:34 all clear/DH:41 DX Severe MFI/ IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2) IVF 2.0-Baseline 11/7/12 beta 0/All Clear Stim start 11/7/12//ER 11/19 11M//10F ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29 stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan Antagonist protacol again Everyone welcome!! My Chart//> Image and video hosting by TinyPic
 
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11-29-2012 at 4:37 PM
jlshapir
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jlshapir is not online. Last active: 05-20-2013, 11:54 AMNewbie

Welcome and MFI does stink!  

Our RE advised us to see a urologist that specialized in MFI before he would treat us, but pretty much indicated IVF w/ ICSI was our only shot and wouldn't even try IUI.  So, that delay treatment for a few months, but gave us time to get more comfortable with IVF as our only shot.  BUT, we do know that there's nothing structurally wrong and his hormones are outstanding, so there's really nothing we can to other than vitamins and supplements.

Hope this helps and good luck! 

 
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TTC #1 since 7/11
Dx: poor ovulation and MFI (low all three)
12/12: IVF#1 w/ICSI
ER: 12/9, 12R/12M/9F; ET: 12/14, transferred 1 perfect 1AA blast, 4 frosties!
+HPT: 12/23, Beta 1 (12dp5dt): 460 (!), Beta 2 (14dp5dt): 1172 (!!), u/s 1: one healthy lima bean with a heartbeat of 161 bpm!
Everyone welcome!
BabyFetus Ticker 
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11-29-2012 at 5:09 PM
LaineyPane...
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We had my issues as well as MFI. After 3 failed IUIs, that's when we had a hysterosalpingogram which showed bilaterally obstructed tubes....so that was our IVF deal sealer.

I understand what you mean about the time and money toward "fixing" the issues with no guarantee....

With so many strikes against us, IVF just made the most sense instead if trying to fix things...
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11-29-2012 at 5:43 PM
futurehube...
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futurehuber is online. Last active: 05-20-2013, 4:29 PMBronze
Thank you so, so much ladies.  Your advice is truly appreciated. Thanks for sharing your stories with me.  And for the warm welcome...looks like I might be hanging out around here for sure sometime soon.  Best of luck to all of you!
TTC #1 since Sept 2011
Me: 33, DH: 35, DX: PCOS & MFI (low everything)
HSG misdiagnosed Bicornuate or Septate Uterus,
but Saline Ultrasound a month later showed no uterine issues, yay!
IUI #1 Oct/Nov 2012: Clomid (100mg) + Trigger + B2B IUIs (2 mil count & 1.8 mil count) = BFN
IUI #2 Feb 2013: Clomid (100mg) + Trigger + B2B IUIs (2.5 mil & 4 mil count) = BFN
IUI #3 March 2013: Clomid (100mg) + Trigger + IUI (5 mil count) = BFN
IVF #1 w/ ICSI: Long Lupron Protocol - Freeze-All Cycle due to Severe OHSS
ER 4/27, 33 Eggs Retrieved, 13 Frosties, Estimated FET 5/29
All are welcome!

3T May Siggy Challenge - Dream Vacation: Northern Italy  
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11-29-2012 at 5:47 PM
futurehube...
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futurehuber is online. Last active: 05-20-2013, 4:29 PMBronze
coastalchristina:

We moved straight to IVF with ICSI due to MFI.  We have <1% chance of getting pregnant on our own or with IUI due to DH's sperm count <5 mil and that IUI would be a waste of our money (OOP for everything).

  DH's horomonal levels were all normal, and the only thing they could find that might be affecting his sperm is that he's a CF carrier.  So the RE and urologist didn't think anything would increase his numbers. 

We had ER yesterday and the fertilization report today was that all 11 mature eggs were fertilized and are doing well.

 Good luck deciding what to do and I hope you get pregnant soon.

GL to you!!  And so great to hear you had a good outcome, very inspiring!  GL!!!

TTC #1 since Sept 2011
Me: 33, DH: 35, DX: PCOS & MFI (low everything)
HSG misdiagnosed Bicornuate or Septate Uterus,
but Saline Ultrasound a month later showed no uterine issues, yay!
IUI #1 Oct/Nov 2012: Clomid (100mg) + Trigger + B2B IUIs (2 mil count & 1.8 mil count) = BFN
IUI #2 Feb 2013: Clomid (100mg) + Trigger + B2B IUIs (2.5 mil & 4 mil count) = BFN
IUI #3 March 2013: Clomid (100mg) + Trigger + IUI (5 mil count) = BFN
IVF #1 w/ ICSI: Long Lupron Protocol - Freeze-All Cycle due to Severe OHSS
ER 4/27, 33 Eggs Retrieved, 13 Frosties, Estimated FET 5/29
All are welcome!

3T May Siggy Challenge - Dream Vacation: Northern Italy  
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