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12-05-2012 at 4:37 PM
djma81
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djma81 is not online. Last active: 05-21-2013, 11:05 AMNewbie

Painful PIO Shots

Any advice on how to help ease the soreness after my PIO injections? Everything was going smoothly with them and I was relieved until they upped my dose from 1cc to 2cc. My poor cheeks are so sore! Is there anyway I can alleviate this? Should I ice before or after? Is sitting on a heating pad okay?
-Me 32...PCOS (no pregnancies) -DDH 43....ASA (2 children from first marriage) -TTC since 9/2011 -2/12 and 3/12 ovulated on Clomid BFN (both months) -4/12 and 5/12 break from trying and focus on our upcoming wedding 5/19/12 and honeymoon to Jamaica!!! Yay!!! -5/7/12 Normal/Clear HSG (very painful for me) -6/11/12 DDH and I decide to begin IVF#1 with upcoming cycle -6/20/12 Mock Transfer and US which showed 2 cysts on Left Ovary -6/11/12 Started OCP's -6/27/12 Repeat US (checking on cyst rupture/growth)....cyst still there! -6/28/12 Surgery to remove the cyst -6/29/12 Rest, and Recovery at home -6/30/12 Recieve Med Shipment -7/1/12 Start Lupron 10mg....cont OCP's -7/7/12 Last OCP....continue Lupron 10 units -7/9/12 Begin STIMS (Gonal-F and Menopur), also Lupron 5 units -7/10/12 PM Lupron 5, Gonal 75, Menopur 75 -7/11/12 AM Gonal 75, PM Lupron 5, Gonal 75, Menopur 75 -7/12/12 AM Gonal 75, PM Lupron 5, Gonal 37.5, Menopur 75 -7/13/12 AM Gonal 75, PM Lupron 5, Gonal 37.5 -7/14/12 AM Gonal 37.5, PM Lupron 5 -7/15/12 PM Gonal 37.5, Lupron 5 -7/16/12 RE cancelled cycle due to drastic drop in E2 -Awaiting AF to hopefully start new cycle in August -Switched RE's -On OCP's x 4 weeks -Last OCP 9/18/12 -Baseline US/Labs 9/21/12 -STIMS begin 9/22/12 -After only 8 days of STIMS (Follistim 150/Menopur 150) had ER 10/3/12....53 Eggs!! -47 mature and 26 fertilized as of day 1 -Moderate OHSS so will wait on transfer....freeze all -10 Frosties...7 day 5 Blasts, and 3 Day 6 Blasts all grades A and B -Start OCP'S 10/11/12 -FET scheduled for 11/29/12!! -1 Expanded Blast Transferred on 11/29/12 -12/10/12 BFN (HPT & Beta) BFN!!! -FET 2 1/31/13 -2/11/13 BFP Beta #1 9.9, Beta #2 2/14/13 0 C/P -WTF Appt 3/28/13 FET#3 6/5/13




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12-05-2012 at 4:41 PM
nawlinsgrl
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You definitely don't want to ice at all.  It's oil, so warmth is what you want, to help it spread out.  A heating pad is a great option.  Also, just make sure to rub the area for a bit immediately after the shot to help it spread.  I forgot to do that during my first couple of shots and ended up with painful knots.  Just rubbing seems to be helping now.
10/10: Married DH; 5/11: Dx: Blocked Fallopian Tube; 7/11: D&C/Hysteroscopy to remove polyp
IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS EDD: 8/23/13
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12-05-2012 at 4:42 PM
JewelsW198...
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Don't ice! I use a heating pad but I'm not going to lie I'm still in a lot of pain too. Make sure you're giving it to yourself in the right spot. Good luck!!
* Me- 32 * DH- 32 * TTC for 4 Years
* *IUIs 1-6 BFN*
*IVF #1= BFP- M/C *FET- * *Beta#1: 69 *Beta#2:482 *Beta#3 1088
*Beta#4 28,318 * Ultrasound- 1 beautiful heartbeat
IT'S A BOY!!! MAX LIAM
 
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12-05-2012 at 4:55 PM
Laurakat81
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Don't inject your cheeks is my best advice! You want hip! Not butt cheek! Seriously, it will cut the pain down to almost nothing!

TTC, Loss, and IF History


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12-05-2012 at 5:06 PM
jadwedd
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I was allowed to ice but I had to warm it up right after, like take a hot shower.  And rub the area.  Still hurt a little but nothing that would stop me :)
Married 12-12-04
TTC since 07
me-36 PCOS, Tubal Problems, and polyps removed 7-12
DH - 36 extremely handsome and no fertility problems
IUI 8-12 and 9-12 failed
IVF 12-21-2012 - 2 I think perfect no matter what the dr graded them (2B)embryos transferred Beta on 12-31-12 Positve - Beta is 21
Beta 2 1-2-13 - 31
Beta 3 1-4-13 - 53
Beta 4 1/9 - 212!
Ultrasound 1/10 - Nothing completely empty uterus Beta 1/14 - 743; Beta 1/17 - 1704 ultrasound shows nothing. Officially a miscarriage. 1/21 Beta 3900 Dr. says it ectopic. Ultrasound shows a miracle heartbeat right in the uterus where it belongs! Dr. says I can be cautiously optomistic!!! Hang in there baby!

 
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12-05-2012 at 5:19 PM
Scoop77
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The massage after the shot was the only thing that made mine feel even a little better. But I'll tell you the truth, I think they get a little sore and achy no matter what. Good luck!

TTC #1 for about 3.5 years
ME: 37, PCO, immune issues?, teflon uterus (my added diagnosis)
HIM: 38, Perfect. (Showoff.)
Month before starting Clomid, spontaneous pregnancy. m/c at 7 weeks and D&C.
Four months of Clomid, one IUI, with Intralipid each cycle: BFNs all
IVF 1.0 July 2012 -- Lupron, bravelle, menopur, estrogen, progesterone supps, intralipid. 14 ER, 14 fertilized, 1 blast transferred, 2 on ice. BFN
FET 1.1 -- 10/2, transferred our 2 blasts. Lupron, PIO, estrogen, baby aspirin, prednisone. BFN.
IVF 2.0 December 2012 -- Bravelle, Menopur, Ganirelix, Prednisone, Metformin, estrogen, progesterone supps. 22 eggs retrieved on 12/14, 17 mature, 15 fertilized. OHSS anticipated so ET cancelled. 3 embryos frozen.
Broke up with old RE. Moving on to new dude. Maybe the change of scenery will be just the trick for our frosties. On BCPs for possible April FET.

P/SAIF welcome 
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12-05-2012 at 5:27 PM
LaineyPane...
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1. Warm the oil in your bra for about 10-15 minutes prior to injection.

2. At the site of injection, have whomever is injecting you DIG their nails in. Seriously, it will take the edge off the needle sting. There will be so much going on there on your cheek that you won't be able to focus on the shot itself.

3. Bend over the edge of a bed or couch for your injection. Put all of your weight on the leg opposite of the side getting injected. Keep the injection leg completely weight free and relaxed as possible. 

4. After the injection, put pressure on the needle site, and then rub for about 5 minutes! 

Those are my tips & tricks for PIO. 

Good luck!

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12-05-2012 at 5:40 PM
J&D2007
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I found it helped me the most to 1.hold the syringe in my or DH hand once the oil was drawn up for 10 minutes or more (I tried warming the bottle and didn't work as well for me) 2. Make sure you have all the muscles relaxed at injection side. 3. Warm after with heating pad.

Me: 35, DH: 36, ttc: 3+ years, dx: unknown
10/11: after 2 years, saw a RE, FSH 5.4
11/11: BFP! (surprise after thyroid med & normal hsg),
12/11: missed m/c after 7 week u/s,
1/12: D&C,
6/12 IUI #1: clomid, 5 mature follicles, excellent sperm,= BFN,
7/12: IUI #2: clomid, 3 mature follicles, excellent sperm= BFN,
8/12: IUi #3: clomid, 5 follicles, = BFP!, C/P
10/12 IVF #1: FSH 5.4, estradiol AFC: 14, long Lupron 150/bravelle75,5R/5M/4F, all 4 made it to 5dt, 1 blast and 1 8 cell transferred. No frosties. BFN
IVF #2: AFC 21, MD lupron 12/25, 225bravelle/150men, 4R/4M/3F, 5dt of 1 blast BFN
IVF #3: natural start antagon, starting 3/30, ER 4/11, 12R,11M,10F
.
[IMG]http://i248.photobucket.com/albums/gg174/pixydust3084/April_V2.jpg%5B/IMG] 
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12-05-2012 at 6:56 PM
CNYBride05
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CNYBride05 is online. Last active: 05-21-2013, 1:40 PMBronze

So I disagree with other posters.  Here's what we do:

1st, make sure you are getting it in the right spot.  Draw (well, have your DH draw) a cross on each cheek, dividing your tush into 4 even quadrants.  The injection should be in the outer/upper quadrant, closest to your hip.  The nurse drew circles for DH after ER and he's just kept re-drawing them daily :-)

Ice for 2-5 minutes before the shot (until the skin feels numbish)/while icing, one of us holds the syringe to warm up the PIO

Wipe injection site with alcohol wipe and let dry

Inject, not quickly, but not too slowly either

Massage with gauze for 5ish minutes

Sit on heating pad (on medium or low) for 15ish minutes

I'm still a little sore, but nothing unbearable.  Hang in there!!  Hope your butt feels better soon! 
Natural m/c Oct. 2005
Dx: balanced translocation and LPD
TTC since Oct 2011
BPF 02/19/12 ----> EDD 10/31/12 ----> natural m/c 02/28/12 (4w6d)
IVF (BCPs starting 10/30/12, ER 11/18/12, 5dt of 1 beautiful, healthy embryo 11/23/12) ----> BFP 12/02/12 ----> Double rainbow, identical twins <3
 
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12-05-2012 at 7:22 PM
djma81
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djma81 is not online. Last active: 05-21-2013, 11:05 AMNewbie
Thanks ladies!! My DH  will be injecting me soon.  
-Me 32...PCOS (no pregnancies) -DDH 43....ASA (2 children from first marriage) -TTC since 9/2011 -2/12 and 3/12 ovulated on Clomid BFN (both months) -4/12 and 5/12 break from trying and focus on our upcoming wedding 5/19/12 and honeymoon to Jamaica!!! Yay!!! -5/7/12 Normal/Clear HSG (very painful for me) -6/11/12 DDH and I decide to begin IVF#1 with upcoming cycle -6/20/12 Mock Transfer and US which showed 2 cysts on Left Ovary -6/11/12 Started OCP's -6/27/12 Repeat US (checking on cyst rupture/growth)....cyst still there! -6/28/12 Surgery to remove the cyst -6/29/12 Rest, and Recovery at home -6/30/12 Recieve Med Shipment -7/1/12 Start Lupron 10mg....cont OCP's -7/7/12 Last OCP....continue Lupron 10 units -7/9/12 Begin STIMS (Gonal-F and Menopur), also Lupron 5 units -7/10/12 PM Lupron 5, Gonal 75, Menopur 75 -7/11/12 AM Gonal 75, PM Lupron 5, Gonal 75, Menopur 75 -7/12/12 AM Gonal 75, PM Lupron 5, Gonal 37.5, Menopur 75 -7/13/12 AM Gonal 75, PM Lupron 5, Gonal 37.5 -7/14/12 AM Gonal 37.5, PM Lupron 5 -7/15/12 PM Gonal 37.5, Lupron 5 -7/16/12 RE cancelled cycle due to drastic drop in E2 -Awaiting AF to hopefully start new cycle in August -Switched RE's -On OCP's x 4 weeks -Last OCP 9/18/12 -Baseline US/Labs 9/21/12 -STIMS begin 9/22/12 -After only 8 days of STIMS (Follistim 150/Menopur 150) had ER 10/3/12....53 Eggs!! -47 mature and 26 fertilized as of day 1 -Moderate OHSS so will wait on transfer....freeze all -10 Frosties...7 day 5 Blasts, and 3 Day 6 Blasts all grades A and B -Start OCP'S 10/11/12 -FET scheduled for 11/29/12!! -1 Expanded Blast Transferred on 11/29/12 -12/10/12 BFN (HPT & Beta) BFN!!! -FET 2 1/31/13 -2/11/13 BFP Beta #1 9.9, Beta #2 2/14/13 0 C/P -WTF Appt 3/28/13 FET#3 6/5/13




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12-05-2012 at 8:56 PM
Crystal120...
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All of this scares the living hell out of me for when I actually have to use it. The bottles are in the closet and I think sometimes the taunt me lol!
Married 9-10-11
Together 6 years before marriage
Me 26 DH 28
TTC since 9/2011
Dx endo 2007 Sx laparoscopy
End bcp 9/2011
Dx annovulatory, DOR, Low AMH
Hysteroscopy due to polyp 2-1-12
IUI#1-3 Cancelled due to low response
IUI#4 BFFN
IVF#1 8/30 Beta#1 256, 8/31 Beta#2 482 BFP!! M/C 5w3d
FET#1 Cancelled due to uterine fluid and thin lining
FET#1.2Cancelled due to abnormal bleeding
Hysteroscopy 12/28/12 All clear
FET#1.3 2/2013 Cancelled
FET #1.4 3/19 BFFN
Good Luck to All!!
Crystal
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12-06-2012 at 10:51 AM
thebrewers...
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Wow, this is all amazing advice!  Saving this post!
Married 2005 | DH & I are 32 | DH diagnosed with CAVD

IVF #1: February 2013
ER 2/13 15R, 12M, 10F
ET 2/18 5DT of 2 beautiful blasts! (none to freeze)
Beta Hell resulted in Chemical Pregnancy
RE shares our concerns about egg quality.
Taking a mental & physical break (with vitamins & weight loss!)

Planning IVF #2 for July or August 2013.

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