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12-10-2012 at 6:25 PM
rocant01
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rocant01 is not online. Last active: 05-16-2013, 6:27 PMNewbie

My Introduction -MTHFR mentioned-

Hello, I have written on other blogs (TTCAL mostly) but I am new to this blog.

My Story My husband and I have been trying to conceive for almost two years now. We finally found out that I do not ovulate on my own and with the help of my OB and meds, we were able to conceive in March 2012. Unfortunately, we miscarried. We continued with the doctor and was able to conceive this August. After 9 weeks, we miscarried again. I had blood work done and found out that I have MTHFR, which is a blood clotting disorder. My OB said it is actually more common than people think. I am taking a baby aspirin and a prescription every day. I am wondering if there is anyone out there with this disorder and if they have had any luck after miscarrying?? I am recently trying again and am not sure when to expect AF since it took 45 days to get the last AF after my DNC.  AF arrived on November 12th and am now anxiously awaiting again to test?  I tested today, which I know is early, but I get so darn impatient! :)  It came up negative but hopefully it is too soon to test. 

 I am not shy and willing to answer any questions about my husband and I's experience with TTC. I am just looking for answers and advice from other people out there! :) Thank you for reading my post. I hope to hear responses. Prayers and thoughts go out to everyone! -Rochelle :) 


Married my wonderful DH on July 16,2011 TTC since July 2011 ~BFP March 2012~ MC :( April 2012~ ~BFP August 2012~ MC/D&C Oct. 2012~ Diagnosed with MTHFR November 2012 
12-10-2012 at 6:32 PM
Beth&Derek
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Beth&Derek is not online. Last active: 05-23-2013, 8:58 PMGold

Welcome! I'm sorry for your losses.

I don't have any info about conceiving after miscarriage, but I also have a clotting disorder (Factor V Leiden) and have a plan with my doctor for when I do get pregnant. I've also been told that it's much more common than I realized. I think miscarriages due to clotting disorders are most common when the disorder hasn't been diagnosed yet.

Best of luck to you!

 

 



Cautiously excited...
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12-10-2012 at 6:34 PM
rocant01
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rocant01 is not online. Last active: 05-16-2013, 6:27 PMNewbie
Thank You!!  GL to you too!! :)

Married my wonderful DH on July 16,2011 TTC since July 2011 ~BFP March 2012~ MC :( April 2012~ ~BFP August 2012~ MC/D&C Oct. 2012~ Diagnosed with MTHFR November 2012 
12-10-2012 at 6:51 PM
mama&baby
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mama&baby is not online. Last active: 05-23-2013, 7:53 PMSilver
rocant01:

 I am wondering if there is anyone out there with this disorder and if they have had any luck after miscarrying?? I am recently trying again and am not sure when to expect AF since it took 45 days to get the last AF after my DNC.  AF arrived on November 12th and am now anxiously awaiting again to test?  I tested today, which I know is early, but I get so darn impatient! :)  It came up negative but hopefully it is too soon to test.   

I am so sorry for your losses....welcome to the board. I don't have experience with this disorder but wanted to wish you luck. I would also recommend posting in 1st tri since most of the ladies here aren't PG (and many haven't had children yet). GL and I hope you have a short stay here! :-)

ETA: Meant to say posting this particular question (if anyone has gotten PG with this disorder after a m/c) in 1st tri.... obviously since you are TTC you should post here!


 Baby Birthday Ticker Ticker Can't decide if we're one and done or we want two! Seeing what happens... not actively TTC now, just keeping track of cycles.  
12-10-2012 at 7:02 PM
kgoldsmith...
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kgoldsmith1023 is not online. Last active: 03-18-2013, 8:10 PMBronze
So sorry for you losses. I hope that your stay on this board is short and sweet!
12-10-2012 at 7:14 PM
Kristinfm
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Sorry for your losses. I don't have any experience with clotting disorders, but wanted to say welcome and good luck!


Me(31) + DH(31) TTC #1 since Dec 2011
CD3 b/w normal, HSG all clear, SA - slightly low morphology, otherwise wnl
RE consult Dec 2012, diagnosed with lean PCOS (didn't see that coming!)
medicated cycles 1 - 4 (Femara 5mg then 7.5mg), = BFN
4/2013 - started metformin, Femara 7.5mg + IUI + progesterone = BFP on 5/7/13!!! EDD 1/16/14
Beta#1 (at 13 DPIUI) 37, Beta #2 (at 15 DPIUI) 103, Ultrasound scheduled for 5/28/13  
12-10-2012 at 7:20 PM
nikkiandch...
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nikkiandchris is not online. Last active: 05-16-2013, 8:53 PMNewbie

I'm so sorry for your losses. I'm going to be purposely a little vague here because I don't want to share my friend's personal details under a screen name that is a little conspicuous...

 A friend has a clotting disorder as well, and after it was diagnosed and treated properly during her most recent pregnancy, she gave birth to a healthy, beautiful baby. I hope that hearing success stories gives you some hope.


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12-10-2012 at 7:24 PM
Stffhappns
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I've not got a lot of experience with MTHFR, aside from taking care of some ladies with it, but I wanted to say welcome to the board.

Dec Siggy Challenge, dream Christmas present: A new professional kitchen! TTC #1 My Ovulation Chart 
12-10-2012 at 7:26 PM
angelchild...
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angelchild24 is not online. Last active: 05-23-2013, 1:57 PMSilver

I am sorry for your losses.

Welcome and good luck!

I do not have any experience with clotting disorders, but I hope that your doc is able to help you get a plan in place that will  lead to a sticky baby for you soon.


BFP 1/30/13 EDD 10/6/13Image and video hosting by TinyPic  BabyFruit Ticker Daisypath Anniversary tickers Lilypie Kids Birthday tickers 
12-10-2012 at 7:33 PM
SnakeFishe...
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SnakeFisherBub is not online. Last active: 05-23-2013, 6:52 PMNewbie

Yikes, sorry for your loss. :(

GL with the testing though, hope you get what you want!


TTGP May Sig Favorite Super Hero: Spider Man http://www.fertilityfriend.com/ticker/4177b3/ttc.png SnakeFisherBubBlog 
12-10-2012 at 7:41 PM
racheldcar...
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racheldcarrell is not online. Last active: 05-23-2013, 11:40 PMNewbie
I'm sorry for your loss. My sister has MTHFR as well, and is 23 weeks pregnant. They thought they were loosing the baby a few weeks ago, but he seems to be growing and getting stronger. This was her first pregnancy, but hope this serves as a success story for you. 

TTC since March 2012 703641_497247786974599_1318392816_o 602828_513255402040504_2045604480_n 
12-10-2012 at 7:51 PM
Sha259
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Sha259 is not online. Last active: 05-10-2013, 9:02 PMNewbie
I have no experience with clotting disorders, nor miscarriage. However, I did want to say I am sorry to hear of your losses. welcome to the boards and I wish you much luck in future cycles.

Anniversary
Me(30) DH(29) TTC since Dec 2011
RE referral Feb 2013 after 14 unsuccessful cycles
Hormones – All clear, Ovarian Reserve – Awesome
HSG – bilateral tubal occlusion, SHG – uterine polyp
SA Mar 2013 – Volume good, Count good, Motility good, Morphology 2% (very low)
RE recommends IVF/ICSI. Plan IVF for 2014
Lap and Hysteroscopy scheduled Jun 2013
SAIF/PAIF very welcome! 
12-10-2012 at 7:57 PM
twolittlew...
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I have no advice or experience, I just wanted to say GL!

DS born 1-24-2010 DD born 7-8-2011 #3 9-1-13

 
12-10-2012 at 9:15 PM
monimu13
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Hi there! I am compound heterozygous for MTHFR, which means that I have one copy of each of the genes.  This was found after my second loss.  RE started me on Folgard, but nothing for clotting as of right now.  I'm kinda new to it all still.  No luck yet though, but my friend with the same mutation just delivered her 4th baby yesterday :)  Good Luck!


TTC #1 since July 2011.
BFP #1: 2/15/12-Ectopic/Mtx at 6 wks
BFP #2 10/12/12-m/c at 5 wks.
HSG all clear!! CD3 b/w normal. Urology appt all clear!
DH:MFI normal count (68mil) low motility (2%) and morph (9%)
Repeat SA: normal count (45.7mil), motility (47%) and low morph (1%), DNA frag: Excellent!
Me:MTHFR:Compound Heterozygous. On High Dose Folic Acid.
Cycle 17: Nov 2012: Clomid+ Trigger+ TI= BFN
Cycle 18: Dec 2012: Clomid+ Trigger+ TI+ progesterone= BFN
Cycle 19: Jan 2013: Clomid+ Trigger+ IUI #1+ TI+ progest =BFN
Cycle 20: Feb 2013: Clomid+ Trigger+ IUI #2+ TI+ progest =BFFN
Cycle 21: Mar 2013: Clomid+ Trigger+ IUI #3+ TI+ progest =BFN
Cycle 22: Apr 2013: Unmedicated TI+ progest =shocking BFN
Cycle 23: May 2013: Unmedicated TI+ progest=
IVF consult done. Waiting for CD 1 for testing, hysteroscopy, and BCP. Cycle in Aug or Sept. Anniversary
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3T May Siggy Challenge-Dream Vacation: Hawaii Image and video hosting by TinyPicImage and video hosting by TinyPic 
12-11-2012 at 7:02 AM
pas1224
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I am so sorry for your loss. I don't have any advice, but wanted to say welcome and good luck.


Anna Catherine 7/23/2012, 35 weeks 5 days, 5lbs 5 oz
IT'S A BOY!!!
 BabyFruit Ticker 
12-11-2012 at 8:33 AM
MJHershey
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Cinci-nasty
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MJHershey is not online. Last active: 05-23-2013, 2:58 PMGold
I am so sorry for your losses. if it helps at all, I know a few people who had success (multiple successes even) after RPL and similar issues. Best of luck, hun!

BIG Congrats NY Mama, Labor Buddy 2010 - now September/December Labor Buddies 2013!

KaramelSutra & MJHershey -Team Caramello- Labor Buddies Sept 2013!

 
12-11-2012 at 8:34 AM
deelopi9
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Miami
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deelopi9 is not online. Last active: 02-05-2013, 8:31 AMBronze
Welcome and I'm so sorry for your losses! I do not have experience with this, however, wanted to wish you the best of luck!

*** TTC since 10/2010 (no planned bc since 2007) Me (31) Sept 2012 - DX Luteal Phase Defect. HSG 8/2012: both tubes are open, cervix and lining look good; hypothyroidism; DH (35) SA Normal Clomid 50mg, trigger
10/2012 BFFN 1st cycle on clomid 50mg w/trigger shot, progesterone level 19.7, cd28 - hcg level 0.
***12/2012 Cycle #25 TTA break until March 2013***
3T Jan2013 Siggy Challenge - Favorite Thing About Winter
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OB/GYN=expertise in pregnancy/labor; RE=expertise in getting pregnant. (read this on someone's post, feel free to PM me to give you credit) I'm so glad I have a RE on my team. Consult a RE after 1 year under 35yo; 6 months 35yo+  
12-11-2012 at 8:35 AM
MJHershey
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Everytime I see MTHFR I think "m*therf*cker!", which i can only imagine is how you feel.

BIG Congrats NY Mama, Labor Buddy 2010 - now September/December Labor Buddies 2013!

KaramelSutra & MJHershey -Team Caramello- Labor Buddies Sept 2013!

 
12-11-2012 at 8:39 AM
tdf2010
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Welcome!!  I'm so sorry for your losses.  I was diagnosed with homozygous MTHFR (C677T) after my second miscarriage.  My RE sent me to a hematologist who recommended I take extra folic acid, baby aspirin, and Lovenox.  I now have an 8 month old daughter!  I'd be glad to answer any questions if you have any!  Good luck!!


My Ovulation Chart

Started TTC #1 08/2010

BFP #1 12/14/2010 EDD 8/24/2011, D&C due to blighted ovum 01/27/2011

BFP #2 05/02/2011 EDD 1/10/2012, MC at 4W2D 05/04/2011

Diagnosed with homozygous C677T MTHFR - Lovenox shots while TTC

BFP #3 08/01/2011 EDD 04/07/2012, DD born 03/29/2012

Started TTC #2 12/2012 on Arixtra due to Lovenox/heparin allergy

BFP #1 03/19/2013 EDD 11/24/2013, MC at 5W 3/24/2013 

12-11-2012 at 9:13 AM
gardennymp...
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I am sorry for your losses. Welcome to the board and good luck!

 BabyFruit Ticker 
12-11-2012 at 10:40 AM
Mrsbtobe20...
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Sorry for your losses. I am new here also.

 

I am also a labor and delivery nurse, and we deliver moms with MTHFR all the time! There is hopeBig Smile


Mrs B's Ovulation Chart

TTC since 10/2012
BFP#1 12/27/12 TWINS!
D&C 2/15/13@ 12 weeks TRAP sequence
TTCAL May Siggy Challenge: Sunflowers
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12-11-2012 at 12:11 PM
RunningGal...
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RunningGal900 is not online. Last active: 05-23-2013, 10:25 PMGold

I am so sorry for your losses.  

I was just diagnosed with the homo version of this mutation. I just started on Folbic tablets (I think that's the same as Folgard) and a baby aspirin daily. My OB said of all the abnormalities she tested me for this is the "best" one to have. I had one completely normal pregnancy two years ago without even knowing this diagnosis followed by ttwo miscarriages this summer/fall. My OB said it is a VERY common mutation that many people have and will just never know they have. She is confident with this course of treatment I can have a successful pregnancy.

The major concern as she explained it to me is that when you can't process folic acid appropriately, you may have increased levels of homocysteine which can lead to clotting. She had me come in for a fasting homocysteine test and she said once I get pregnant again I will be monitored to ensure that my homocytesteine levels stay in the normal range. The biggest concern is keeping your homocysteine levels in check.  

Best of luck to you! 


BFP#1-7/28/2010, DS-4/11/2011
BFP#2-7/21/2012, MM/C-8/9/2012
BFP#3-11/1/2012, M/C-11/25/2012
BFP#4-1/16/2013, EDD-9/29/2013 My 4th BFP chart: My Ovulation Chart Lilypie Maternity tickers 
01-01-2013 at 6:06 PM
rocant01
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rocant01 is not online. Last active: 05-16-2013, 6:27 PMNewbie
Thank you so much for that success story!  Every little bit of positive words goes a long way!! :)

Married my wonderful DH on July 16,2011 TTC since July 2011 ~BFP March 2012~ MC :( April 2012~ ~BFP August 2012~ MC/D&C Oct. 2012~ Diagnosed with MTHFR November 2012 
01-01-2013 at 6:28 PM
curlylocks...
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curlylocks3 is not online. Last active: 05-24-2013, 12:43 AMSilver
I'm sorry for your losses. I don't have MTHFR but I do know that treatment can vary based on which genes you have, if you're heterozygous or homozygous for it. It sounds like you're already being treated but the only other advice I have is to ask your OB for a referral to speak to an MFM or perinatologist if you haven't already. They would be able to give their recommendations on treatment during pregnancy/ TTC and answer any questions you have. 
I have Leiden Factor V and had that referral and found it reassuring. I don't have stats in front of me but many women with clotting disorders do go on to have healthy pregnancies. Good luck, welcome, and I am here if you have other questions or just want to chat.


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О Привязать! Z!
TTC since 11/2011
BFP #1 EDD 12/14/12, C/P 4/9
Me: 27, dx DOR, heterozygous Leiden Factor V; H: 28, no known issues
After 3 failed Clomid + IUI cycles we are moving on to IVF in July
Everyone welcome. 
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