I take mine with a glass of milk in the mid morning or afternoon. Anytime I took them with food or on an empty stomach I got really sick. Typically I take mine about 2 hours after I breakfast.
It helps me to drink tons of water through the day.
DO NOT take them right before bed!! Even if I didn't vomit I would wake up and dry heave (even though my dr told me that was the best time to take them).
The break might not have helped you any, either. I notice that if I forget a day the next dose always sits harder. So, it might be a good idea to get yourself in a routine so your body gets used to it.