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01-02-2013 at 9:51 AM
Daysie
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Joined on 10-24-2002
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Daysie is not online. Last active: 05-19-2013, 4:49 PMGold

PGS Results.

We had 7 embryos left from our IVF and FET cycles. We finally decided, with the push of our RE, to go ahead to do PGS on the remaining embryos. This ment thawing, biopsying, and re-freezing the 7 embryos. Thankfully, all 7 made it through the thaw and back to re-freeze. Last week, the day after Christmas, we got the results back. 3 of the 7 were abnormal. 1 had one less chromosome, 1 had one extra chromosome, and the last one had 2 extra chromosomes. All 3 of those were boys. This leaves us with 4 normal embryos in the hopes they make it through another thaw at this point. We will be meeting with our RE tomorrow to find out if it would be best to utilize the last cycle we have with insurance coverage as a full IVF cycle again, instead of a FET. (Our insurance counts FET's as IVF cycles).

I'm ok with this news and with the amount of embryos still left. But I am concerned about how this thaw and re-freeze will affect them.

We also found out the sex of the remaining 4 embryos. We have 3 girls and 1 boy. And we also were finally able to find out what the twins were, they were girls.

I'm hoping tomorrow will help guide us in the right direction and help us. If we are doing a FET, I will be starting the Lupron on the 6th. If we switch to a full IVF cycle, I may not be able to start until next month since the office does all the cycles in groups.  

So, that's the latest update with me. The Holidays were crazy busy. I hope everyone had a wonderful Holiday season with friends and family!  

♥TTC#1 since June 2010♥

BFP #1 - 2/14/2011 * Natural m/c - 2/28/2011 @5w4d
BFP #2 -7/9/2012 * Chemical Pregnancy
BFP #3 -10/12/12 * Missed m/c - 11/15/12 @8w4d
BFP #4 - 2/18/13 * EDD 11/1/13! Please Stick Around Little One!

♥My Chart♥
DH (31) - 06/2011 - All Normal!
Me (29) - Stage 2 endo, polyps, cysts, and septum, FSH- 7.8, AMH - 1.2.
Hysteroscopy/Lap - 11/17/11 - removed: Stage 2 Endo, 3 cysts, and polyps & septum fixed.
1/1/12 -Cycle #18 = Ovidrel+B2B IUI+Progesterone = BFN
1/28/12- Cycle # 19 = Ovidrel+B2B IUI #2+Progesterone = BFN
4/6/12 - Stims Begin!! 300 Follistim, 10 Novearel, ganirelix
4/16/12- Cycle Cancelled. Poor/Late responder
6/8/12 - Stims begin for IVF 1.2: 500 Follistim, 20 Novarel, Ganirelix
6/18/12 - Trigger
6/20/12 - ER = 20 Retrieved, 18 mature, 15 fertilized w/ICSI
6/25/12 - ET - One beautiful blast transferred. 9 to freeze
7/9/12 - Beta #1 = 450, 7/11/12 - Beta #2 = 350, 7/13/12 - Beta #3 = 198-chemical pregnancy
8/23/12 - Hysteroscopic Surgery scheduled - Adhesion removed.
9/2/12 - FET Cycle #1 - tfr'ed 2 5 day blasts, 1 hatching
10/5/12 - ET
10/10/12 - + HPT FX for a sticky baby!
11/2/12 - 2nd U/S - 1 ges sac, 2 beautiful babies 2 beautiful heart rates = 125!!
11/15/12 - 8 weeks, no heart beats
11/16/12 - D&E - Chromosome testing showed 2 normal females
12/17/12 - Embryos biopsied and sent for PGS and re-frozen.
12/26/12 - PGS results: 3 abnormal male embryos, 4 normal embryos remaining.
1/6/13 - Lupron start for FET #2.
1/17/13 - Baseline - Cyst delayed us by a week.
1/25/13 - Baseline #2
2/7/13 - Lining Check
2/13/13 - FET #2 - tfr'ed 2 5 day blasts
2/18/13 - BFP! +HPT, Please, Please stick little one(s)
2/26/13 - Beta #1 = 1361!! keep sticking little one!
2/28/13 - Beta #2 = 2787!! Thanks Be To GOD!!
3/2/13 - Beta #3 = 4959! What a little miracle we have!
Lilypie Maternity tickers
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My Blog

vote on my names TTGP Info for Newbies

P/SAIF Welcome 
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01-02-2013 at 10:27 AM
DoublePort...
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DoublePortion is not online. Last active: 05-20-2013, 9:34 PMSilver
I'm sorry to hear about the 3, but glad the 4 are ok. FX they do just fine with the thaw. Prayers that your appt tomorrow gives you a clear cut answer as to which decision is best. ((hugs))
Image and video hosting by TinyPic
Me: 29 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
AMH .97 as of 4/2012!
Him: 27 ~ perfect swimmers
Laparotomy with partial oophorectomy 8/2009 to remove cysts/endo. Stopped BC 4/2010.
Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
Occasionally using acupuncture.
IVF #1:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embies txfrd. ~ BFN
BCP to manage Endo from 10/2012 to 12/2012.
PAIF/SAIF always welcome!

If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus! 
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01-02-2013 at 10:30 AM
MJ14323
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MJ14323 is not online. Last active: 05-20-2013, 10:14 PMBronze

That's great you have 4 normal embryos.  Best of luck in your next step.

 We will also be doing PGS testing due to my low AMH.  It's crazy how much they can tell so early on.

TTC since Nov 2010 | Me: 28, DH: 29 | SA & HSG Normal
IF Treatment started December 2011
Late DX DOR after 10 months of treatment | AMH-.23, FSH-11.1
Stag II Endo removed in July 2012
5 Rounds of Clomid(50-150mg), TI & IUI#1 = BFNs
3 Rounds of Femara(5mg) & Prog, TI, IUI#2, IUI#3 = BFNs
Supplements include DHEA, CoQL, L-Caratine, Vitamin C/D/B3, Fish Oil, and Prenatal
March IVF cycle canceled due to cyst
April IVF #1 - Lupron, Saizen, Menapur, Gonal-F, baby aspirin and dexamethasone | AFC 8 >> 9R, 4M, 2F w/ ICSI...looking to do PGS testing...Stopped dividing at day 3.
Retested AMH, dropped to undetectable at <.16.
Trying to decide what to do next...
Everyone Welcome
My Blog
 
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01-02-2013 at 10:30 AM
SteFizzRic...
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I'm so sorry again for your loss. I'll be thinking of you tomorrow and hope you end up with a direction that you are comfortable with. It's great that you still have 4 embryos frozen that you know are healthy and normal!  

If you were to do a fresh cycle, would you re-do the PGS testing on those embryos?
**TTC #1 since 10/2010**
Me~28 DH~29
*u/s & b/w dx PCOS 05/2011*
1/2012 RE Consult
1/2012-3/2012: 3 cycles of Clomid + Ovidrel + TI = BFN
4/2012: 100mg Clomid + Ovidrel + IUI #1 = Canceled, zero sperm
Repeat SA Confirms Azoo

*DH dx Azoo due to CUAVD(R) & obstructed Vas(L)*
9/2012- mTESE: Sperm Found & 12 Vials Frozen

10/2012: MiniIVF w/ICSI: Beyaz, Clomid, Gonal F, Nasal Spray Trigger
10/1 - Start BCP for 14 days
10/18 - Stims: 50mg Clomid & 75iu Gonal-F
10/30- Trigger w/ Syranel Nasal Spray
11/1 ER: 3R, 2F & 1 pending
11/8: 1 grade B blastocyst frozen
11/19 Hysteroscopy
12/8: Begin Estradiol & Prometrium
12/13 FET = BFN

PAIF/SAIF Welcome!



Much love to my 73 3TFB!  
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01-02-2013 at 10:35 AM
lincoln79
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Joined on 10-24-2011
1,463 Posts
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lincoln79 is not online. Last active: 05-20-2013, 11:18 PMBronze

glad you got results that you can work with. hopefully, it will save some future heart-ache, you've had enough already.

as someone who does freeze/thaw cycles on cell samples often, if it is done right (e.g. not by my students, but by your RE's lab, lol), the impact is minimal. 

hoping for the best for you!

we are planning on FET #2 on Feb.1 (on bcps now), so maybe we will be cycle buddies. 
TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own. 3 Failed IUI's (2/2012, 4/2012, 6/2012) IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d Praying unceasingly for a miracle. PAIF/SAIF welcome Image and video hosting by TinyPic Image and video hosting by TinyPic Image and video hosting by TinyPic  
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01-02-2013 at 12:10 PM
Daysie
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Joined on 10-24-2002
Maryland
8,692 Posts
24,126 Points
Daysie is not online. Last active: 05-19-2013, 4:49 PMGold
SteFizzRich:

I'm so sorry again for your loss. I'll be thinking of you tomorrow and hope you end up with a direction that you are comfortable with. It's great that you still have 4 embryos frozen that you know are healthy and normal!  

If you were to do a fresh cycle, would you re-do the PGS testing on those embryos?

 

If we do a fresh cycle, more than likely we will be sending those out for PGS as well. I've had enough heart-ache, and if we can try our hardest to prevent more, we will do anything we can. I know that PGS isn't a 100% grantee, but it can give a little more help in trying to prevent. I wasn't really sure if we should do it in the first place since the testing on the twins from my last loss came back normal. At this point we still have a lot of other things to consider, and more than likely I'm dealing with implantation issues. 

♥TTC#1 since June 2010♥

BFP #1 - 2/14/2011 * Natural m/c - 2/28/2011 @5w4d
BFP #2 -7/9/2012 * Chemical Pregnancy
BFP #3 -10/12/12 * Missed m/c - 11/15/12 @8w4d
BFP #4 - 2/18/13 * EDD 11/1/13! Please Stick Around Little One!

♥My Chart♥
DH (31) - 06/2011 - All Normal!
Me (29) - Stage 2 endo, polyps, cysts, and septum, FSH- 7.8, AMH - 1.2.
Hysteroscopy/Lap - 11/17/11 - removed: Stage 2 Endo, 3 cysts, and polyps & septum fixed.
1/1/12 -Cycle #18 = Ovidrel+B2B IUI+Progesterone = BFN
1/28/12- Cycle # 19 = Ovidrel+B2B IUI #2+Progesterone = BFN
4/6/12 - Stims Begin!! 300 Follistim, 10 Novearel, ganirelix
4/16/12- Cycle Cancelled. Poor/Late responder
6/8/12 - Stims begin for IVF 1.2: 500 Follistim, 20 Novarel, Ganirelix
6/18/12 - Trigger
6/20/12 - ER = 20 Retrieved, 18 mature, 15 fertilized w/ICSI
6/25/12 - ET - One beautiful blast transferred. 9 to freeze
7/9/12 - Beta #1 = 450, 7/11/12 - Beta #2 = 350, 7/13/12 - Beta #3 = 198-chemical pregnancy
8/23/12 - Hysteroscopic Surgery scheduled - Adhesion removed.
9/2/12 - FET Cycle #1 - tfr'ed 2 5 day blasts, 1 hatching
10/5/12 - ET
10/10/12 - + HPT FX for a sticky baby!
11/2/12 - 2nd U/S - 1 ges sac, 2 beautiful babies 2 beautiful heart rates = 125!!
11/15/12 - 8 weeks, no heart beats
11/16/12 - D&E - Chromosome testing showed 2 normal females
12/17/12 - Embryos biopsied and sent for PGS and re-frozen.
12/26/12 - PGS results: 3 abnormal male embryos, 4 normal embryos remaining.
1/6/13 - Lupron start for FET #2.
1/17/13 - Baseline - Cyst delayed us by a week.
1/25/13 - Baseline #2
2/7/13 - Lining Check
2/13/13 - FET #2 - tfr'ed 2 5 day blasts
2/18/13 - BFP! +HPT, Please, Please stick little one(s)
2/26/13 - Beta #1 = 1361!! keep sticking little one!
2/28/13 - Beta #2 = 2787!! Thanks Be To GOD!!
3/2/13 - Beta #3 = 4959! What a little miracle we have!
Lilypie Maternity tickers
Image and video hosting by TinyPic
My Blog

vote on my names TTGP Info for Newbies

P/SAIF Welcome 
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01-02-2013 at 12:21 PM
liz4paws
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FX for your four embryos. I can't imagine what a rollercoaster ride it has been for you. Big hugs, Daysie!
Me (31) DH (35) - Finding our path to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR
DH: Severe MFI
12/2/11 - IUI #1- BFN
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
My ovaries seem to be just for decoration

12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - Thawed four, sadly two didn't survive. Transferred two beautiful blasts.

2/16/13 - First BFP of my life!
3/27/13 - No heartbeat at 9w0d. D&C the following day.

4/23/13 - Matched to adopt five new embryos!

My embryo adoption blog: Wishing on a Snowflake

Lilypie Angel and Memorial tickers

 
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01-02-2013 at 1:06 PM
daiseydood...
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I am so sorry for you loss. I hope your PGS embies bring you your take home baby. GL
TTC since 9/10 consult 1/12 All testing came back fine Diagnosed with Unexplained infertility All treatments OOP 3 medicated IUI's All BFN IVF - ER 11/14 24R, 15M, 13F ET 11/19, BETA 11/28 BFFN --Next step FET in Jan ET scheduled for 1/24. Beta #1 350 Beta #2 735. U/S Hell. miscarriage D&C at 9weeks. FET #2 ET 5/28 Beta 6/6. Everyone welcome Image and video hosting by TinyPic  
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01-02-2013 at 2:45 PM
rrdiva1
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Oh sweetie, I am so sorry to hear about the 3, but happy to hear about the other ones. What a trip to know so much info upfront like that. It is such a miracle with pregnancy, so many factors.

That is interesting that your ins. counts FET as a cycle. I am keeping my FX for you at your RE appointment tom. that everything gets on the right track. Biggest hugs ever!!!! <3
Married BF 6/29/2002/ TTC Since Aug 2011/ ME:34 all clear/DH:41 DX Severe MFI/ IVF w/ICSI OCT 2012 Stims started 10/8/ER 10/19/12/ET 10/24/Beta#1 11/2=BFN (beta was 1.2) IVF 2.0-Baseline 11/7/12 beta 0/All Clear Stim start 11/7/12//ER 11/19 11M//10F ET 2 embies 11/24//Beta#1 28 Beta #2 23 Beta#3 29 stop meds Beta#4 37/C/P 5W5D EDD:8/12/13/IVF#3 in Jan Antagonist protacol again Everyone welcome!! My Chart//> Image and video hosting by TinyPic
 
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01-02-2013 at 7:11 PM
ball.and.c...
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DoublePortion:
I'm sorry to hear about the 3, but glad the 4 are OK. FX they do just fine with the thaw.  ((hugs))

This.  Good luck!

Married my wife 8/2007 *** TTC #1 since 7/2011
4 IUIs w/ midwives = 4 BFNs
5 IUIs w/ an RE = 5 BFNs
IVF October/November 2012
ER 11/1: 22 eggs retrieved, 17 fertilized!
ET 11/6: 1 blast transferred, 5 frozen
BFP 11/15! Beta #1: 104 Beta #2: 613 Beta #3: 3415
Blighted ovum discovered at 7w5d; D&E 12/13
FET 1 cancelled
FET 1.1: ET 4/30: 1 blast transferred
BFP 5/7! Beta #1: 142 Beta #2: 730 Beta #3: 3100
*Everyone welcome*

BabyFruit Ticker 
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01-02-2013 at 11:59 PM
chucktgirl
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I am so happy for you that you have 4 chances ready! I hope they work for you! I am shocked at all the information you got from PGS! I was told only that all of my tested embryos had "severe abnormalities". I wasn't told the sex or ANYTHING else about them! I think now I want to go back and ask this info! Anyway, I am wishing good things for you and your FET!!! :)

My (old) BLOG: www.ivfbabyquest.wordpress.com
TTC since Jan 2010 with OPKs. Me: 41, Hypothyroidism, hetero MTHFR C677T, hetero Factor V Leiden (no previous clots) Dx: DOR due to AMA. Rx: 100mg Levothyroxin, FaBB tab, Spring Valley Prenatal Vitamins, Vitamin D. Hubby: 34, Hyperthyroidism, Fragile X carrier, Great swimmers!
Natural PG 9/27/11; MC at 8wks. Used Cytotec to expel: 1/20/12 (unpleasant)
First RE visit: 8/8/12, Saline Sonogram: 8/28/12(4cm unknown mass in upper left of uterus) 2nd Saline Sonogram: 10/2/12 (mass disappeared!) IVF injection class: 10/11/12
IVF #1: 10/17/12 Baseline: FSH- 9.4, E2- 24, LH- 3.7, Progesterone- 0.3. 6 follicles in my right ovary & 9 in my left. Rx: 150 Bravelle & 150 Menopur SQ in AM. 10/21/12: Add Ganirelix SQ in PM. 10/26/12: hCG Trigger IM. ER 10/28/12: 13R, 7M, 6F. 5 Made it to PGS. ET 11/2/12: CANCELED. PGS: All 5 have "severe abnormalities." Devastated. Begged RE for back-to-back IVFs; Started Provera 11/2/12. AF said FU and came anyway, destroying any chance for a Dec IVF. Maxed out lifetime IF meds insurance. I can barely breathe, waiting to get through this process, hoping for my take-home-baby.
IVF #2: 1/7/13 Baseline: FSH- 8.8, 4 follicles in my right ovary & 6 in my left. Rx: 150 Bravelle & 150 Menopur SQ in PM. 1/11/13: Add Ganirelix SQ in AM. 1/16/13: hCG Trigger IM. ER 1/18/13: 9R, 5M, 5F. 2 Made it to PGS. ET 1/23/13: CANCELED. PGS: All embryos have "multiple severe abnormalities." RE recommends we stop trying and focus on living childless, due to the repeated extremely poor quality of my eggs. I don't even know what to do with that.
IVF #3- NEW RE! 100% OOP: 3/1/13 Baseline: FSH- 9.6, E2- 61, Progesterone- 0.94, 3 follicles in my right ovary & 4 in my left. Rx: 150 Bravelle & 150 Menopur SQ in PM. 3/7/13: Add Ganirelix SQ in AM. hCG Trigger 3/9/13 SQ. 3/11/13 ER: 6R, 2M, 2F. Day 3: one 8 cell, grade 0. 3/16/13 Five day ET: one early blast, grade Fair. 3/24/13 Started period a day before beta. BFN.
IVF #4 (FINAL) (Added acupuncture to this cycle.): 3/25/13 WTF & Baseline: FSH-11.8, E2- 56, Progesterone- 0.84 3/26/13 Start stims. 3/30/13 u/s: 5 follicles in my right ovary & 4 in my left. Rx: 225 Bravelle & 225 Menopur SQ in PM. 3/31/13 Add Ganirelix SQ in AM. hCG Trigger 4/3/13 SQ. 4/5/13 ER: 5R, 3M, 3F naturally. Day 3: two 8 cell, grade 0, one 8 cell, grade 2 (Scale 0-best to 3-worst). 4/10/13 Five day ET: two blastocysts (the 3rd stopped growing.) 4/18/13 Beta: 2.5 BFFN.
No DE or adoption for us, FIRM.
That’s it for us. I am beyond devastated and have no idea how to proceed from here. My life has been forever altered by this experience. Best wishes to all in their journeys! 
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