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01-08-2013 at 8:31 PM
RosyGlow
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Joined on 11-30-2012
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RosyGlow is not online. Last active: 05-25-2013, 1:52 PMBronze

IVF Cycle and FET Timing Question

Hi ladies, 

I'm learning a lot from all of you, so up front I really want to thank you for sharing your knowledge here. As you may recall, I am new to all of this. We are planning a freeze-all IVF cycle this spring (fingers crossed there will be healthy embryos to freeze, of course) I am hoping to do a frozen egg transfer in May sometime if we get healthy embryos to freeze. I am curious about a couple of things on timing. Sorry if these are terrible questions - I'm just really new to all of this. If there is a good resource out there for me to learn more about "the basics" I can take a look at that for sure. Feel free to link me or recommend books/articles. 

-How soon after an IVF cycle for egg retrieval will AF usually show up (therefore re-starting my cycle, right?) 

-If the first FET is not successful, how long do most RE's/women choose to wait before trying another FET? 

-I am not sure whether we will choose to do a medicated cycle or a natural cycle following egg retrieval or not. How does this choice impact the timing of FET following the IVF retrieval process? 

-Essentially, if the first attempt at FET doesn't work, when would the soonest second FET likely be possible?  

Thanks in advance... 


| Married since 2008 | DH and I: Both 30 | | Me: Endometriosis DH: Low Morph | | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 frozen embryos. Freeze-All IVF#2: May 2013. Our PGD probe will be completed in early May. Hoping for healthy embryos and an FET this summer.



Everyone Welcome!  
01-08-2013 at 8:35 PM
Crystal120...
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Crystal120410 is not online. Last active: 05-25-2013, 10:01 AMBronze

Every RE is different. Some require breaks in between cycles, some every three cycles and one no breaks at all. My RE will let me try again as soon as AF shows up. 

I don't know anything about natural cycles.

Im not sure about AF after retrieval since I went through ET and 2ww.

good luck! 


Married 9-10-11
Together 6 years before marriage
Me 26 DH 28
TTC since 9/2011
Dx endo 2007 Sx laparoscopy
End bcp 9/2011
Dx annovulatory, DOR, Low AMH
Hysteroscopy due to polyp 2-1-12
IUI#1-3 Cancelled due to low response
IUI#4 BFFN
IVF#1 8/30 Beta#1 256, 8/31 Beta#2 482 BFP!! M/C 5w3d
FET#1 Cancelled due to uterine fluid and thin lining
FET#1.2Cancelled due to abnormal bleeding
Hysteroscopy 12/28/12 All clear
FET#1.3 2/2013 Cancelled
FET #1.4 3/19 BFFN
Good Luck to All!!
Crystal
Image and video hosting by TinyPicImage and video hosting by TinyPic Daisypath Anniversary tickers
 
01-08-2013 at 8:40 PM
RosyGlow
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Joined on 11-30-2012
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RosyGlow is not online. Last active: 05-25-2013, 1:52 PMBronze
Thanks, Crystal. I appreciate it. I didn't realize that every RE is different. Also, I wanted to say that I appreciated your post yesterday - the one with the poem from her book. You are very thoughtful and insightful, even in spite of your clearly difficult journey with fertility. Hang in there, and thanks again. 

| Married since 2008 | DH and I: Both 30 | | Me: Endometriosis DH: Low Morph | | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 frozen embryos. Freeze-All IVF#2: May 2013. Our PGD probe will be completed in early May. Hoping for healthy embryos and an FET this summer.



Everyone Welcome!  
01-08-2013 at 8:50 PM
JGior1031
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Joined on 11-14-2008
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JGior1031 is not online. Last active: 05-23-2013, 6:27 PMBronze
Hi! I'm new to all of this too and am about to start my first IVF cycle.
I'm sorry if this is a silly question but why would you have a freeze all cycle and not a transfer right away?
Best of luck to you!



Boscorelli AKA "Bosco"
Me: 30 DH: 34 DX: Severe MFI 2 failed IUI's
Starting our IVF journey Jan/Feb '13
IVF #1 ER 2/11/13- Retrieved 3 eggs and all 3 Fertilized!
ET 2/14/13 Transfered 2 perfect 8 cell (one Grade A one Grade AB) Come on Valentines Baby!!!
Positive HPT on 2/22/13!!!! BFP!!!
2/25/13 Beta #1 474 @ 11dp3dt
2/27/13 Beta #2 1553 @ 13dp3dt
EDD November 4th, 2013!!!
1st Ultrasound 3/6/13 showed 2 beautiful sacs!! IT'S TWINS!!!!!!
2nd ultrasound 3/15/13 We heard the heartbeats!! Baby A 117bpm & Baby B 115bpm

 Pregnancy Ticker
 BabyFruit Ticker
 IAmPregnant Ticker 
01-08-2013 at 9:21 PM
RosyGlow
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Joined on 11-30-2012
19,609 Points
RosyGlow is not online. Last active: 05-25-2013, 1:52 PMBronze

JGior1031:
Hi! I'm new to all of this too and am about to start my first IVF cycle. I'm sorry if this is a silly question but why would you have a freeze all cycle and not a transfer right away? Best of luck to you!

Hi JGior! Glad there are other newbies. Good question! Here is how I understand it. We are doing PGD (preimplantation genetic diagnosis because I carry a disorder that we want to avoid passing on to our children). The PGD process requires a biopsy from the 5-day embryos' trophectoderm (the outside edge of the embryo which eventually turns into the placenta if the embryo becomes a pregnancy). This process requires additional time, from what I understand. Also (and our bigger reason for not doing a fresh transfer), my RE supports the idea of doing an FET in order to avoid OHSS and also to provide the best possible recovery from the egg retrieval. The lab/clinic we are using is very skilled in the freezing/thawing process, which is why this doesn't present any additional risk for us or our *hopeful* future embryo's (according to my RE, anyway). My RE described the process of doing a Freeze-All as her preference for our situation because she thinks it will allow my body to recover from the egg retrieval and get back to a healthier state for supporting a pregnancy. 

I know someone who went through the PGD process as well, and in her experience, the first transfer (fresh) was a BFN. She attributes it to her OHSS and also that her body was not in a very balanced "welcoming-to-embies" state. Her second transfer, an FET a couple months later, was a BFP. :) 

So essentially, our RE said we could choose to do a fresh transfer, but that she wouldn't recommend it.  


| Married since 2008 | DH and I: Both 30 | | Me: Endometriosis DH: Low Morph | | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 frozen embryos. Freeze-All IVF#2: May 2013. Our PGD probe will be completed in early May. Hoping for healthy embryos and an FET this summer.



Everyone Welcome!  
01-08-2013 at 11:06 PM
solisilou
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15,580 Points
solisilou is not online. Last active: 05-25-2013, 2:11 PMBronze
Hi, welcome to the board and to ask as many questions as you like.
About FET timing I can only talk about my experience. I'm doing now my third FET and the last two FETs were in October and November. If Xmas hadn't come in the way, I would have done number three in December also. My FET cycles only include an hcg trigger and progesterone supps afterwards, so not that much medication. I guess that's why my RE allows me doing btb FETs.

I hope you have a great stim cycle and get a lot of frosties!

Me 32 / DH 36
TTC since 08/2010
Me: Lap in 2007 due to pelvic pain: Dx mild endo
Lap in 2011: ovarian cyst and endo removal
2 Clomid cycles: good response but both BFN
borderline high anti-cardiolipin IgM Abs - now on baby aspirin
DH: S/A very low all three - unexplained

IVF/ICSI #1: 06/2012 11R/11M/9F 2dt of one 4-cell embie - BFP,
beta hell, U/S hell, m/c and D&C at 9w6d
FET #1: 10/2012 3dt of one 10-cell embie - BFN
FET #2: 11/2012 2dt of one 2-cell embie - BFN
FET #3: 01/2013 3dt of one 6-cell embie - BFN
IVF/ICSI #2: 02/2013 14R/13M/7F 5dt of one blast 2/16 - BFP,
beta hell, m/c at 5w3d
FET #4: 04/2013 5dt of 2 morulas - BFN
FET #5: 05/2013 5dt of 2 morulas -


 
01-09-2013 at 8:11 AM
JGior1031
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Joined on 11-14-2008
7,941 Points
JGior1031 is not online. Last active: 05-23-2013, 6:27 PMBronze
RosyGlow:

JGior1031:
Hi! I'm new to all of this too and am about to start my first IVF cycle.
I'm sorry if this is a silly question but why would you have a freeze all cycle and not a transfer right away?
Best of luck to you!

Hi JGior! Glad there are other newbies. Good question! Here is how I understand it. We are doing PGD (preimplantation genetic diagnosis because I carry a disorder that we want to avoid passing on to our children). The PGD process requires a biopsy from the 5-day embryos' trophectoderm (the outside edge of the embryo which eventually turns into the placenta if the embryo becomes a pregnancy). This process requires additional time, from what I understand. Also (and our bigger reason for not doing a fresh transfer), my RE supports the idea of doing an FET in order to avoid OHSS and also to provide the best possible recovery from the egg retrieval. The lab/clinic we are using is very skilled in the freezing/thawing process, which is why this doesn't present any additional risk for us or our *hopeful* future embryo's (according to my RE, anyway). My RE described the process of doing a Freeze-All as her preference for our situation because she thinks it will allow my body to recover from the egg retrieval and get back to a healthier state for supporting a pregnancy. 

I know someone who went through the PGD process as well, and in her experience, the first transfer (fresh) was a BFN. She attributes it to her OHSS and also that her body was not in a very balanced "welcoming-to-embies" state. Her second transfer, an FET a couple months later, was a BFP. :) 

So essentially, our RE said we could choose to do a fresh transfer, but that she wouldn't recommend it.  


Wow! Thank you for that answer. I learn something new everyday with this whole process.
Best of luck to you and welcome!



Boscorelli AKA "Bosco"
Me: 30 DH: 34 DX: Severe MFI 2 failed IUI's
Starting our IVF journey Jan/Feb '13
IVF #1 ER 2/11/13- Retrieved 3 eggs and all 3 Fertilized!
ET 2/14/13 Transfered 2 perfect 8 cell (one Grade A one Grade AB) Come on Valentines Baby!!!
Positive HPT on 2/22/13!!!! BFP!!!
2/25/13 Beta #1 474 @ 11dp3dt
2/27/13 Beta #2 1553 @ 13dp3dt
EDD November 4th, 2013!!!
1st Ultrasound 3/6/13 showed 2 beautiful sacs!! IT'S TWINS!!!!!!
2nd ultrasound 3/15/13 We heard the heartbeats!! Baby A 117bpm & Baby B 115bpm

 Pregnancy Ticker
 BabyFruit Ticker
 IAmPregnant Ticker 
01-09-2013 at 10:25 AM
PurpleIris...
Not Ranked
Joined on 01-21-2011
10,471 Points
PurpleIris30 is not online. Last active: 05-25-2013, 10:50 AMBronze
RosyGlow:

JGior1031:
Hi! I'm new to all of this too and am about to start my first IVF cycle. I'm sorry if this is a silly question but why would you have a freeze all cycle and not a transfer right away? Best of luck to you!

Hi JGior! Glad there are other newbies. Good question! Here is how I understand it. We are doing PGD (preimplantation genetic diagnosis because I carry a disorder that we want to avoid passing on to our children). The PGD process requires a biopsy from the 5-day embryos' trophectoderm (the outside edge of the embryo which eventually turns into the placenta if the embryo becomes a pregnancy). This process requires additional time, from what I understand. Also (and our bigger reason for not doing a fresh transfer), my RE supports the idea of doing an FET in order to avoid OHSS and also to provide the best possible recovery from the egg retrieval. The lab/clinic we are using is very skilled in the freezing/thawing process, which is why this doesn't present any additional risk for us or our *hopeful* future embryo's (according to my RE, anyway). My RE described the process of doing a Freeze-All as her preference for our situation because she thinks it will allow my body to recover from the egg retrieval and get back to a healthier state for supporting a pregnancy. 

I know someone who went through the PGD process as well, and in her experience, the first transfer (fresh) was a BFN. She attributes it to her OHSS and also that her body was not in a very balanced "welcoming-to-embies" state. Her second transfer, an FET a couple months later, was a BFP. :) 

So essentially, our RE said we could choose to do a fresh transfer, but that she wouldn't recommend it.  

I don't know the specifics of your single gene disorder, but for ours we can do a Day 3 biopsy, and then a day 5 transfer.  If we were to opt to do a chromosomal screening (also called CGH or PGS, depending on the type of screening) in addition to the single gene testing, then we would need to do a day 5 biopsy, freeze all, and then transfer later. I'm not saying that all single gene defects can be done with a Day 3 biopsy, but for our particular situation, it is possible.


Married 8/2008. IVF with PGD March 2013.
3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!
 
01-09-2013 at 5:17 PM
RosyGlow
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Joined on 11-30-2012
19,609 Points
RosyGlow is not online. Last active: 05-25-2013, 1:52 PMBronze

PurpleIris - this is a great question. We ARE opting to do PGS along with our PGD. Perhaps this is another reason why she is recommending the freeze-all cycle. Her main reason is that she thinks my body will respond better once it has recovered from the egg retrieval process. Does the 3-day biopsy utilize the traphectoderm, or does it remove a cell from the 5/6cell embryo? I'm still learning, as you can see. This is such a complicated process.Thanks for your response. I hope we will end up cycling at the same time...we shall see. 


| Married since 2008 | DH and I: Both 30 | | Me: Endometriosis DH: Low Morph | | Planning IVF with PGD and PGS in 2013 | Freeze-All IVF #1: March 2013 ER 3/26. 29R, 12M, 11F. 4 frozen embryos. Freeze-All IVF#2: May 2013. Our PGD probe will be completed in early May. Hoping for healthy embryos and an FET this summer.



Everyone Welcome!  
01-09-2013 at 6:18 PM
PurpleIris...
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Joined on 01-21-2011
10,471 Points
PurpleIris30 is not online. Last active: 05-25-2013, 10:50 AMBronze
RosyGlow:

PurpleIris - this is a great question. We ARE opting to do PGS along with our PGD. Perhaps this is another reason why she is recommending the freeze-all cycle. Her main reason is that she thinks my body will respond better once it has recovered from the egg retrieval process. Does the 3-day biopsy utilize the traphectoderm, or does it remove a cell from the 5/6cell embryo? I'm still learning, as you can see. This is such a complicated process.Thanks for your response. I hope we will end up cycling at the same time...we shall see. 

 Ah - yes that makes sense.  The Day 3 biopsy removes one cell from the embryo.  If doing a Day 5 biopsy, they can remove more cells and get more genetic material, which is necessary (as I understand it) if doing a full cgh chromosomal screen.  After talking with our RE, we've decided not to do CGH in addition to our PGD, although if we wanted to do CGH we would have had to do a freeze-all with transfer later.


Married 8/2008. IVF with PGD March 2013.
3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!
 
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