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01-17-2013 at 12:44 PM
starspangl...
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Joined on 01-17-2013
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starspangledgirl1 is not online. Last active: 05-09-2013, 8:48 PMNewbie

E2 is up today-why arent follies growing??

Hi all, Im on day 5 of stims and went for my check this AM.... my RE just called and said my E2 shot up in 2 days from 192 to 628, but my follies are still 8-12 mm. They've been creeping up the whole time but its slow. does the rise in e2 mean more growth is coming soon?

 

me 40 (almost 41), DH 39

FSH: 8.6, AMH: 2.3, AFC: 15 at baseline-everything "normal"

TTC since 2009 when I was 37, secondary infertility
Male factor: double varicocele, now 3-4 yrs later, I probably have aging eggs, not diagnosed with DOR yet though.

DS: 4/29/05 

MC: 9/12/11

7/12 IUI #1 -Gonal F Pen: 75-150, BFN (only 1 measurable follicle produced)
8/12 IUI #2 -BFN Gonal F pen: 150 BFN (only 1  measurable follicle produced)
NEED A BREAK ALREADY!!!!

TTC au natural...not happening. Ugh. When will my little guy get his sibling???

1/2013: IVF #1 Antagonist Prot. BCP for 2 weeks, Gonal F 300/Menopur 150, AFC baseline 10. Currently stimming, looking ok, 10 measuable follicles btwn 8-12mm, long road ahead.  


me 40, DH 39... FSH:8.6 AMH 2.3 AFC:15... DH: MF: sx for Double Varicocele, SA 45 mil, motil: 50%, morph 3%- "lazy swimmers!"... Me: All "normal" but aging eggs most likely... ;-/ DS: 4/29/05-7 yrs old MC 9 weeks: 9/21/11 TTC for 3 yrs...7/2012: 1st IUI: BFN 8/2012: 2nd IUI: BFN... Need a break already! IVF #1 in progress Jan 2013: Antagonist Prot.: Gonal F 300/Menopur 150 ER: 15 follies, 12 retrieved, 10 mature, 10 fertilized...grow embies grow! 1/8/13: BFN.  
01-17-2013 at 12:48 PM
Crystal120...
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Joined on 04-24-2011
29,883 Points
Crystal120410 is not online. Last active: 05-21-2013, 9:10 PMBronze
How many do you have? Its 200 per mature follicle.

Married 9-10-11
Together 6 years before marriage
Me 26 DH 28
TTC since 9/2011
Dx endo 2007 Sx laparoscopy
End bcp 9/2011
Dx annovulatory, DOR, Low AMH
Hysteroscopy due to polyp 2-1-12
IUI#1-3 Cancelled due to low response
IUI#4 BFFN
IVF#1 8/30 Beta#1 256, 8/31 Beta#2 482 BFP!! M/C 5w3d
FET#1 Cancelled due to uterine fluid and thin lining
FET#1.2Cancelled due to abnormal bleeding
Hysteroscopy 12/28/12 All clear
FET#1.3 2/2013 Cancelled
FET #1.4 3/19 BFFN
Good Luck to All!!
Crystal
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01-17-2013 at 12:54 PM
starspangl...
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Joined on 01-17-2013
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starspangledgirl1 is not online. Last active: 05-09-2013, 8:48 PMNewbie
hi crystal...there are 13 total: 1- 12mm, 3- 11mm, 1- 10mm, 1 -9mm, 1 -8mm, 1 -7mm, and 5 smaller ones.....around 6mm. 

me 40, DH 39... FSH:8.6 AMH 2.3 AFC:15... DH: MF: sx for Double Varicocele, SA 45 mil, motil: 50%, morph 3%- "lazy swimmers!"... Me: All "normal" but aging eggs most likely... ;-/ DS: 4/29/05-7 yrs old MC 9 weeks: 9/21/11 TTC for 3 yrs...7/2012: 1st IUI: BFN 8/2012: 2nd IUI: BFN... Need a break already! IVF #1 in progress Jan 2013: Antagonist Prot.: Gonal F 300/Menopur 150 ER: 15 follies, 12 retrieved, 10 mature, 10 fertilized...grow embies grow! 1/8/13: BFN.  
01-17-2013 at 12:56 PM
nawlinsgrl
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Joined on 10-28-2009
21,933 Points
nawlinsgrl is not online. Last active: 05-21-2013, 10:11 PMBronze

***PAIF/SAIF***

I just checked my notes from my 2 IVF cycles, and noticed that I didn't hit E2 numbers that high until 2-4 days later than you, but both times my follies were in the range you mentioned.  The first time, my biggest was 13.5 and the second time the biggest was 11.  

I had far more eggs in that second cycle too (20 vs 12 in the first), so it sounds to me like everything is progressing appropriately. 

Based on your age, you can expect to stim a little longer than younger folks.  It took me 13 days both times, but it was worth it.  Slow and steady really does win this race.  I know it's hard to wait things out, but it will be worth it once it's over.

Good luck to you!


10/10: Married DH; 5/11: Dx: Blocked Fallopian Tube; 7/11: D&C/Hysteroscopy to remove polyp
IVF #1: 9/11: ER: 12R, 11M, 10F, No Frosties; 5dt: 2 blasts, 1 morula; DD born 6/3/12
IVF #2: 11/12-12/12: ER: 20R, 20M, 16F, 4 Frosties; 5dt: 3 blasts, DS EDD: 8/23/13
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01-17-2013 at 1:06 PM
Mayan2011
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Joined on 01-16-2011
6,114 Points
Mayan2011 is not online. Last active: 05-19-2013, 10:49 PMSilver
It sounds like you have many smaller ones coming online.  So you are likely looking at two different cohorts of follies.  I am famous for this.  It will be up to your RE if they will go after the first or second cohort, or to try and get some from both.  Sometimes this means sacrificing some of the larger ones to try and mature more of the smaller ones.  GL.

DH:41 Me:34
Dx: MFI (very low everything)
IVF/ICSI Only Option

IVF #1 (antagonist): 01/2011: 9ER; 8M; 5FN; 3(3dt) = BFN
IVF #2 (agonist): 05/2011: 13ER; 12M; 8FN; 2(3dt) = BFP (1 frostie)
+HPT 8dp3dt; Betas: #1 12dp3dt=174; #2 19dp3dt=3461; u/s 7w5d = heterotopic pregnancy = 2 D&Cs for uterine (Trisomy 16) and meds to dissolve ectopic
IVF #3 (agonist w BCP): 12/2011: 10ER; 9M; 8FN; 2(5dt)= BFP (2 frosties)
+HPT 4dp5dt; Betas: #1 9dp5dt=363; #2 11dp5dt=896; B/G Twins - c/s at 37wks2d due to HELLP Syndrome
 
01-17-2013 at 3:52 PM
new+tothis
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Joined on 07-18-2012
16,825 Points
new+tothis is not online. Last active: 05-21-2013, 10:11 PMBronze
Mine shot up the same way between day 3 and 4. It went from like 150 to 700ish. I was also on the antagonist protocol. My RE didn't even seem phased by it. Didn't change dosing or anything. I had about 12-15 that were all around 8-10mm. I think they estimated I had 20-25 follies total at that point. Then they changed to 30-35 after a different monitoring appt but I ended up with 25. I think they just jump like that.

TTC #1 for Dh, #2 for me. HSG clear. Low AMH and endo. Multiple Clomid w/TI cycles - all BFNs. 2 IUIs with Clomid and 1 with Femara - more BFNs. IVF#1 25R, 15M, 15F. 5DT of two perfect 4AA blasts! Positive HPT at 5dp5dt. Beta #1 6dp5dt - 72. Beta #2 8dp5dt - 285. Beta #3 10dp5dt - 793. Both babies have strong beautiful heartbeats! Baby B miscarried at 7 weeks. Baby A is holding on through miscarrying her twin, sub-chorionic hematoma, and complete placenta previa. Stick, baby, stick!

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01-17-2013 at 4:45 PM
Gr8te
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Joined on 08-18-2012
10,004 Points
Gr8te is not online. Last active: 05-21-2013, 10:13 AMBronze
I'm not sure, but I think it means your lining is preparing for ovulation. I could be wrong but when my E2 went from 12 to 2000 in one day. I was told I would probably have to do a freeze all because my uterus was preparing for ovulation but my eggs weren't ready yet.

~ Everyone Welcome ~
TTC: 05/2011 Me: 32, All Clear DH: 38 Dx: MFI Low Testosterone & 1% Morphology
IVF #1 w/ICSI & IMSI, 12/03/12: ER: 27R, 20M, 15F
4 blasts frozen (3BA 4BA 4BB 5BB) b/c of moderate OHSS
FET #1: 02/08/13 Transferred 3BA & 4BA | HPT 5dp5dt BFP!
10dp5dt Beta #1 - 810 | 12dp5dt Beta #2 - 1843
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