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02-20-2013 at 11:41 AM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
23,633 Points
BzeetyD is not online. Last active: 06-18-2013, 10:13 PMSilver

EPP cycle length/semi technical question (free pizza for real answers)

Formerly I was on BCPs in my prep cycles prior to our 3 IVFs. This time I'm on EPP.

In a BCP cycle I knew my cycle would be 28 days exactly. With EPP, is this also true? Is that what the Estrace and Cetrotide do in combination post surge?

I'm offering a slice of hot cheesy digital wee pizza for real answers ---> like this Pizza

Thanks.

 


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
02-20-2013 at 11:43 AM
HarleyP11
Not Ranked
Joined on 09-14-2008
12,449 Points
HarleyP11 is not online. Last active: 06-18-2013, 10:27 PMBronze
I just did an EPP. I started estrace on CD 20 and my cycle was 29 days. It's usually 28 days. Hth!!!

TTC # 1
Me: Hashimotos Disease, Elavated Prolactin, Uterine Polyps DH: SA good
12/11: HSG polyps found; 1/12: 1st apt with RE; 1/12: SHG: polyps confirmed, 2/12: diagnosed with Hashimotos, prescribed synthroid; Elevated prolactin, MRI clear, prescribed Dostinex; 2/12: hysteroscopy & D&C
3/2012 unmedicated cycle= BFN
4/2012 trigger + iui + endometrin=BFN
5/2012 Ovaries look "PCO-Like". Finally able to trigger on CD28. Trigger + TI + Endometrin = BFN
6/2012 Follistim + Trigger + iui = BFN
7/2012 Follistim + Trigger + iui = BFN
Unmedicated cycles 8/2012 & 9/2012=BFN
10/2012 IVF#1 = BFP 9dp3dt Beta=20, 14dp3dt Beta=9 C/P
IVF#2 Estrogen Priming Protocol beginning 1/14/2013
Beta 7dp5dt 117, Beta 9dp5dt 223, Beta 12dp5dt 583
1st Ultrasound 2/28 showed two yolk sacs!
Lilypie Pregnancy tickers 
02-20-2013 at 11:45 AM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
23,633 Points
BzeetyD is not online. Last active: 06-18-2013, 10:13 PMSilver

HarleyP11:
I just did an EPP. I started estrace on CD 20 and my cycle was 29 days. It's usually 28 days. Hth!!!

Thank you, ma'am!

Pizza 


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
02-20-2013 at 11:53 AM
joules12
Not Ranked
Joined on 06-30-2009
Southern New Jersey
13,982 Points
joules12 is online. Last active: 06-18-2013, 11:26 PMSilver

During my EPP go-round, my 30-day cycle remained the same.

(oh how I wish that pizza was real!!!)


TTC since honeymoon in 9/2010
Me: 38, Dx DOR (FSH = 10.5, AMH = 0.43, best AFC = 10), AMA
MH: 37, Dx Obstructive Azoospermia, multiple successful sperm retrieval procedures

1/2012: IVF/ICSI #1 Antagonist = cancelled d/t poor response to max stims
2/2012: IVF/ICSI #2 MDLF (4R, 4M, 1F) = BFP, saw heartbeat, missed m/c 9w0d, D&E
8/2012: IVF/ICSI #3 EPP/MDLF (7R, 2M, 1F) = BFN

12/2012: (New RE) Operative hysteroscopy to remove scar tissue

1/2013:IVF/ICSI #4 Low-dose stim/Antagonist (AFC=6); ER=1/26 (5R-couldn't access rt ovary, 5M, 4F), ET=1/29 (trans 3) = BFP!; 2/11 beta#1(13dp3dt)=2127, 2/13=3367
Twin girls due 10/19/13

PAIF/SAIF very welcome!  BabyFruit Ticker 
02-20-2013 at 12:46 PM
brooklynes...
Not Ranked
Joined on 08-10-2011
11,732 Points
brooklynesque is not online. Last active: 06-18-2013, 9:26 PMSilver
The estrogen and ganirelix shortened my luteal phase by about 4 days. It really took me by surprise. But my protocol might have been different; estrogen patches starting day 21, ganirelix for three days starting I think day 22.

Me: 39. DH: 41. TTC since 2009.
FSH: 9.5 at highest. AMH (11/2011): 0.9. AFC: 10ish. HSG: Normal. SA: Normal.
July 2011 - Feb. 2012: 2 Clomid/TI cycles; 3 injectables/IUI cycles. Good response but BFNs.
Dec. 2011: Laparoscopy (clear) + hysteroscopy to remove uterine polyp.

April 2012: IVF #1: FSH 9.2, AFC 7-8. Antagonist protocol.
Started stims (300iu Gonal-F, 150iu Menopur) 3/28.
Added ganirelix 4/1. Trigger 4/5 (7 follies). ER 4/7: 7R, 0M, 0F. :-(

Nov. 2012: IVF #2: Long Lupron protocol.
Started Lupron 10/27. AFC 10+. Started stims (300iu Follistim, 150iu Menopur) 11/8.
Trigger 11/18 (7 follies). ER 11/20: 9R, 1M, 1F. 3dt of my one 6-cell embie on 11/23: BFN.

Dec. 2012: Hail Mary IUI cycle with leftover IVF meds: BFN.

Feb. 2013: IVF #3: Estrogen priming protocol.
Pre-AF: estro patch + ganirelix. AFC 8-10. Started stims (450 Follistim, 150 Menopur) 1/28.
Added ganirelix 2/4. Combined Lupron/HCG trigger 2/10 (6-ish follies).
ET 2/12: 6R, 1M, 1F w/rescue ICSI. My embie didn't make it. :-(

July 2013: DE IVF #1

PAIF/SAIF/PA35 welcome.

Daisypath Anniversary tickers 
02-20-2013 at 1:29 PM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
23,633 Points
BzeetyD is not online. Last active: 06-18-2013, 10:13 PMSilver
joules12:

During my EPP go-round, my 30-day cycle remained the same.

(oh how I wish that pizza was real!!!)

Thanks lady! Pizza


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
02-20-2013 at 1:29 PM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
23,633 Points
BzeetyD is not online. Last active: 06-18-2013, 10:13 PMSilver

brooklynesque:
The estrogen and ganirelix shortened my luteal phase by about 4 days. It really took me by surprise. But my protocol might have been different; estrogen patches starting day 21, ganirelix for three days starting I think day 22.

Thanks - I'm on pills not patches, so maybe kind of the same? Here you are! Pizza


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
02-20-2013 at 3:35 PM
Edwina.McD...
Not Ranked
Joined on 12-09-2009
16,015 Points
Edwina.McDunnough is online. Last active: 06-18-2013, 11:29 PMGold
Neither estrogen or the antagonist should change your luteal phase; any changes while on EPP are not due to those particular meds because they don't effect your progesterone production. What they do is shut down your ovaries so that no preliminary follicles can start to grow (your body normally starts recruiting follies in your LP) and thus, when you actually start your stims, your antral follicles are all close to (or closer to) the same size, thus discouraging lead follicles. Because you're suppressed, many people on EPP will stim longer and slower than on a straight non-suppression cycle. For me the difference was a few days longer.

Something about how estrogen works: your developing follicles naturally make estrogen. It's what makes your lining plump up and also what makes your body shut off it's FSH production. Interrupring this feedback loop is how Clomid and Letrozole work to get your body to overproduce FSH. This is also why cd3 FSH values need to be interpreted with E2 in mind. If your E2 is unnaturally high because of a cyst or because that's how your body rolls, it will make your FSH unnaturally low and make you appear more fertile than you really are. When you are doing EPP your cd3 E2 will be pretty high and your FSH will be really low, like maybe less than 3.

Digi pizza is gluten free, dairy free and deelicious I assume?

+++ 
02-20-2013 at 4:13 PM
BzeetyD
Not Ranked
Joined on 07-29-2010
Twin Cities, MN
23,633 Points
BzeetyD is not online. Last active: 06-18-2013, 10:13 PMSilver
Edwina.McDunnough:
Neither estrogen or the antagonist should change your luteal phase; any changes while on EPP are not due to those particular meds because they don't effect your progesterone production. What they do is shut down your ovaries so that no preliminary follicles can start to grow (your body normally starts recruiting follies in your LP) and thus, when you actually start your stims, your antral follicles are all close to (or closer to) the same size, thus discouraging lead follicles. Because you're suppressed, many people on EPP will stim longer and slower than on a straight non-suppression cycle. For me the difference was a few days longer.

Something about how estrogen works: your developing follicles naturally make estrogen. It's what makes your lining plump up and also what makes your body shut off it's FSH production. Interrupring this feedback loop is how Clomid and Letrozole work to get your body to overproduce FSH. This is also why cd3 FSH values need to be interpreted with E2 in mind. If your E2 is unnaturally high because of a cyst or because that's how your body rolls, it will make your FSH unnaturally low and make you appear more fertile than you really are. When you are doing EPP your cd3 E2 will be pretty high and your FSH will be really low, like maybe less than 3.

Digi pizza is gluten free, dairy free and deelicious I assume?

WINNER WINNER CHICKEN DINNER! Thanks for the explanation. I like to know how and why things work. 

This pizza is free of all that stuff, but comes with extra pixels. 

Pizza

Thanks again.


BzeetyD = 37, Mr. BzeetyD = 43 together 12/02 married 9/08
TTC #1 since 1/10
DX: Unexplained/MFI issues

Our lil' lost sparks:
5w3d loss 7/30/10 - EDD March 2011
8w loss 4/15/11 - EDD November 2011
8w3d loss 8/2/12 - EDD March 2012
4w c/p loss 10/29/12 - EDD July 2012

Long story: trying on our own + testing testing testing with 6 rounds of Clomid, more testing, injectables + TI, laparoscopy - one tube blocked, 2 IUIs with Follistim...BFNs.
RPL testing all normal, Karyotyping normal

Moving on to IVF.

IVF #1 April 2012 = BFN, IVF #2 June 2012 = BFP. U/S 7/23 = saw heartbeat but measuring behind. Follow up U/S on 7/30 - no heartbeat. D&C 8/2. Trisomy 12. IVF #3 Oct 2012 = Chemical Pregnancy

Phone consult with CCRM on 12/12/12 - ODWU 1/4/13 - both tubes clear(!) - AFC 24, AMH 3.2, FSH 9.6, LH 5.4, E2 25. DH has high frag rate but improved!
IVF #4 March 2013 CCRM. EP protocol w/ Menopur, Gonal-F & Dexamethasone. ER 3/29 & IMSI, PICSI. 43R 13M 10F 6blasts bio'd. CCS testing reveals 3 normals!!!
FET 5/31/13 of 1 4AA blast - thawed and expanded. 4dp5dt BFP.
Beta 9dp5dt = 181, 11dp5dt = 427




"I'm not telling you it's going to be easy, I'm telling you it's going to be worth it."

Everybody is welcome!!!  
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