I had a friend get a Staph Infection while she was still in the hospital after her delivery with an Epi. After a long recovery, they realized the doctor had nicked her bowel while doing the Epi. He also had four other cases where this happened to women.
She said this past summer (four years later) she finally feels like everything is healed (she had to get a few surgeries) and she is actually finally thinking about having #2, but will most likely request a C-section if she can.
I keep forgetting to ask my doctors their opinion on Epi's, but if I do have to get one, I said I will lay there with my eyes closed and say, "Please don't nick my bowel, please don't nick my bowel" repeatedly.